Monk Fruit Extract Powder; Mogroside V 88901-36-4; Siraitia Grosvenorii Extract(SGE); Momordica Grosvenorii Extract

Native to Guangxi, China, Monk Fruit Extract is becoming a favorite in the global health food industry for its high sweetness, zero calories, and multiple health benefits. Siraitia grosvenorii is a natural sweet ingredient extracted from the traditional Chinese medicine monk fruit. Its sweetness can reach 300 times that of sucrose without generating any heat. This precious natural sweetener not only possesses excellent sweet properties but also retains the traditional healthcare effects of Siraitia grosvenorii, such as moistening the lungs, relieving cough, smoothing the intestines, and alleviating constipation._[1] Monk fruit (Momordica grosvenorii) is a unique medicinal and edible plant widely used in China across various industries, including food and beverages, healthcare, and cosmetics. Furthermore, the global sugar reduction trend is creating an unprecedented market opportunity for its extract, thanks to its natural, zero-calorie sweetness.

Monk fruit is a perennial herbaceous vine belonging to the genus Siraitia of Cucurbitaceae, which grows in mountainous areas with an altitude of 300-500 meters. The stem is slender, dark purple, and 2-5 meters long; Leaves are heart-shaped, ovate, membranous, 8-15 cm long, 3.5-12 cm wide; Flowers are dioecious. The fruit is spherical or oblong in shape, with 10 longitudinal lines, initially densely covered with yellow brown hairs and mixed with black glandular scales. The skin is thin and easily brittle after drying; The seeds are pale yellow, nearly round or broadly ovate in shape. Siraitia grosvenorii is a vine, not a tree. Its fruit is low-temperature dried after ripening for use in medicine or extract production.
Monk fruit extract has a 1000-year history of medicinal use in China. It is traditionally used to clear heat, moisten the lungs, and relieve constipation. In recent years, with the progress of extraction technology, the application value of mogroside as a natural sweetener has been fully developed.

Leading domestic enterprises, including Layn Corp and Giffords, have made significant breakthroughs in monk fruit extraction technology and established a comprehensive production process. The traditional technological process of monk fruit extract is: raw medicinal materials → pretreatment → extraction → concentration → microfiltration → ultrafiltration → nanofiltration → spray → drying → sterilization → packaging.

• Raw material pretreatment stage:

Selected ripe monk fruit, after cleaning, impurity removal, and crushing treatment; Using low-temperature drying technology (40-50 ℃) to maintain the active ingredients; Grind to 40-60 mesh particles to increase the extraction contact area

• Extraction stage:

Combining modern extraction techniques:
①Water extraction method: extract 2-3 times in a cyclic manner at 60-80 ℃
②Enzyme-assisted extraction: adding cellulase and pectinase (pH 4.5-5.0, 45-55 ℃)
③Ultrasonic assisted extraction: frequency 40kHz, power 500W, time 30min
④Microwave assisted extraction: power 400-600W, time 5-10 minutes

• Purification and refining stage:

Using macroporous adsorption resins (such as AB-8, HPD100) for separation and purification
①Membrane separation technology: ultrafiltration (MWCO 10-50kDa) and nanofiltration (MWCO 200-400Da)
②Vacuum concentration: temperature ≤ 60 ℃, concentration to 15-20 ° Brix
③Spray drying: inlet air temperature 180-200 ℃, outlet air temperature 80-90 ℃

• Quality control stage:

HPLC detection of Mogroside V content ≥ 10%; Indicators such as heavy metals and pesticide residues comply with USP and EP standards

Mogrosides are the main active components of Monk Fruit Extract/Siraitia Grosvenorii Extract/Momordica Grosvenorii Extract, which belong to triterpenoids and are unique chemical components of Momordica grosvenorii. Among them, Mogroside V has the highest content, which is a non-sugar substance with a strong sweet taste.

The physical properties of mogroside include:
Smell: It has a unique aroma of monk fruit
Taste: sweet, with a sweetness equivalent to 250-300 times that of sucrose
Solubility: Easy to dissolve in water, good solubility
Stability: It does not deteriorate in weak acids or bases, and has good thermal stability

Mogroside V is zero-calorie. It does not raise blood sugar levels, making it an ideal natural sweetener for individuals with diabetes and health-conscious consumers.

051 Regulating blood glucose and lipid-lowering effects
Research indicates that monk fruit extract has significant effects on regulating blood sugar balance. As a non-sugar sweetener, this ingredient doesn't participate in human metabolism and doesn't cause blood sugar level fluctuations, which makes it an ideal sweet substitute for diabetes patients.

The experimental results of Liu and other researchers showed that the fasting blood glucose value, serum insulin level, and glycosylated serum protein index of diabetes model mice were significantly reduced after ingesting high-dose mogrosides. The study observed a significant enhancement in insulin tolerance and a rise in anti-atherosclerotic blood lipids._[4] Notably, mogrosides V indicate efficacy in preventing tissue damage and inhibiting muscle atrophy. It enhances carbohydrate metabolism efficiency and modulates body fat levels through its core mechanism.
Zhang's research team further confirmed that the low-polarity glycosides extracted from the fresh fruits of monk fruit, which are composed of mogrosides IIA1, IA1, and III, have obvious hypoglycemic effects. This discovery has opened up a new research direction for exploring other biological activities of monk fruit extract._[5]

052 Antioxidant and anti-inflammatory properties
Monk fruit extract has a strong scavenging ability against hydroxyl radicals and superoxide anion radicals. The experimental results showed that siraitia grosvenorii extract (SGE) had no toxic effect on HaCaT and HSF cells in the concentration range of 0.5% to 5.0%, and could promote cell proliferation. In addition, SGE can significantly inhibit the secretion of the inflammatory cytokine IL-6 in HaCaT cells and reduce the generation of reactive oxygen species (ROS), indicating both anti-inflammatory and antioxidant activities. In terms of skin anti-aging, SGE induces the secretion of PIP-1 in HSF cells, which enhances skin elasticity and firmness. When combined with L-Arg, it can significantly upregulate the expression level of HBD-2 mRNA in HaCaT cells, thereby boosting skin immune function._[6] 
Other studies have pointed out that siraitia grosvenorii extract can also play a systemic anti-inflammatory role through the gut spleen axis, and its mechanism may be related to the active ingredients contained in it, such as kaempferol; These components inhibit the activation of signaling pathways such as PI3K-AKT, IL-17, and TNF by acting on core targets such as AKT1, CASP3, MMP9, EGFR, and PTGS2._[7]

053 Moisturizing the lungs, relieving cough, and protecting the liver
Traditional Chinese medicine believes that monk fruit extract can invigorate the body, clear heat, moisten the lungs, dispel fire, smooth the intestines, and relieve constipation. It is widely used in the treatment of sore throat and cough. Modern research demonstrates that mogroside V offers liver protection and prevents liver fibrosis. The study clarified the effective components of Siraitia grosvenorii at the level of small molecular metabolites, that is, the improvement and regulation mechanism of Siraitia grosvenorii extract and mogroside V (MV) on allergic pneumonia, found out the corresponding metabolic pathway, and determined that mogroside V (MV) is the main effective component to alleviate allergic asthma pulmonary inflammation from the metabolic level._[8]

Siraitia grosvenorii extract/Monk fruit extract is primarily used in three fields: food and beverage, medicine and health products, and other industries. In the market in 2024, food and beverage applications are forecasted to lead the Siraitia grosvenorii extract market, holding a substantial share. The pharmaceutical and health product sectors are also expanding rapidly, driven by the diverse biological activities of Siraitia grosvenorii extract, such as antioxidant, hypoglycemic, and immune-regulating functions.

• Food and beverage industry

Siraitia grosvenorii glycoside, as a natural high-power sweetener, is widely used in:
①Beverages: various sugar-free beverages, sports drinks, fruit juice drinks, etc
②Desserts: sugar-free candies, chocolates, ice cream, etc
③Seasoning: A Sweet balance of salty foods such as soy sauce and seasoning sauce

• Medical and health products

Based on its traditional efficacy and modern pharmacological research, Momordica grosvenorii glycosides are used for:
①Throat moistening products: relieve discomfort and hoarseness in the throat
②Moisturizing and laxative products: improve constipation and intestinal health
③Blood glucose management products: help diabetes patients control blood glucose
④Immune enhancement products: improve the body's resistance

• Cosmetics and skincare products

Recent research found that the combination of monk fruit extract with human β-defensin-2 inducer (such as arginine) has a dual regulatory effect on skin immunity, with good anti-inflammatory effect and the function of improving skin immunity.

Monk fruit extract can be divided into different types according to the content of mogroside V, more than 50% mogroside V, and others. Products with more than 50% mogroside V currently dominate the global market, accounting for 64% of total sales._[2]
From the perspective of product form, Momordica grosvenorii extract is primarily divided into two forms: liquid and powder.

The acceleration of the global sugar reduction trend has brought huge market opportunities for mogroside. As a natural, zero-calorie sweetener that does not cause changes in blood sugar, siraitin just meets the needs of modern consumers for a healthy diet. In the future, the application field of mogroside will be further expanded, especially in sports nutrition supplements, anti-inflammatory agents, intestinal flora regulators, and new drug carriers. It is predicted that the total market size of 80% Momordica grosvenorii extract in China will increase from US $7 billion in 2025 to US $15 billion in 2030, more than doubling. This growth is mainly due to the improvement of health awareness, the continuous increase in demand, and the promotion of innovative technologies in the industry. The application growth in the field of functional foods and beverages is particularly significant, with an expected compound annual growth rate (CAGR) of 20%.[3]

As a natural, safe, and multifunctional sweetener, Momordica grosvenorii extract not only meets people's pursuit of sweetness but also provides an ideal solution for a healthy lifestyle. From blood sugar management to immune regulation, from food and beverages to healthcare products, this natural gift originating from China is safeguarding the health of global consumers.

	Proven Expertise & Global Reach Nasdaq-listed(Nasdaq: BON) manufacturer with 19+ years in herbal extract production and 19+ years of export experience; Products are distributed to over 100 countries, and extensive participation in international exhibitions.
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	End-to-End Quality Control Raw Material Selection: Procurement with full traceability; Advanced Production: 100,000-Class cleanrooms, triple-core technologies (ton-scale extraction, heavy metal removal, enzymatic purification) meeting FDA/EU standards; Rigorous Testing: The QC department conducts strict inspections from raw materials to finished products.
	R&D & Customization Capabilities PhD-led R&D team (>50% hold advanced degrees) with cutting-edge equipment (e.g., molecular distillation, nanofiltration); Custom formulations, packaging, and OEM solutions; factory audits accepted; no trader involvement.
	Robust Supply Chain High Capacity: 50+ technicians, multiple production lines, daily output exceeding 1,000 tons; Fast Delivery: 80% of orders are shipped immediately; global logistics network (EU/US) with door-to-door multimodal transport; Inventory Efficiency: 40+ SKUs across 4 product lines, 1,000+ tons of inventory for flexible fulfillment.
	Competitive Cost Structure Factory-direct pricing reduces procurement and logistics costs. Partnerships with packaging and logistics providers ensure cost-effective solutions.
	Cutting-Edge Testing Lab Equipped with HPLC, atomic absorption spectrometers, UV spectrophotometers, etc. Full-spectrum testing for heavy metals, microorganisms, and compliance with global regulations.

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Tags: Monk Fruit Extract Powder; Mogroside V; Siraitia Grosvenorii Extract(SGE); Momordica Grosvenorii Extract, manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk

Reference:

[1]Chen Yao. Study on Chemistry and Function of Siraitia grosvenorii[D]. Shanghai:Shanghai Jiao Tong University, 2005.
[2]https://www.gelonghui.com/p/1649159
[3]https://max.book118.com/html/2025/0227/8015073125007035.shtm
[4]LIU Hesheng,QI Xiangyang,YU Keke, et al. AMPK activation is involved in hypoglycemic and hypolipidemic activities of mogroside-rich extract from Siraitia grosvenorii(Swingle)fruits on highfat diet/streptozotocin-induced diabetic mice[J].Food&function,2019,10(1):151-162.
[5]ZHANG Yulong,ZHOU Guisheng,PENG Ying,et al. Anti-hyperglycemic and anti-hyperlipidemic effects of a special fraction of Luohanguo extract on obese T2DM rats[J].Journal of Ethnopharmacology,2020,247:112273-112280.
[6]Lu Bining, Kim Yiseul, KiM Jonggun, et al. The Enhancement of Skin lmmunity and Inhibition of Inflammatory Aging by Siraitia grosvenorii Extraction[J]. Biological Chemical Engineering, 2024, 10(06):26-30.
[7]Zhang Jin, Wu Huining, Zhao Linlu, et al. To Explore Anti-Inflammatory Mechanism of Momordicagrosvenori Extract Based on Network Pharmacology andMolecular Docking[J]. Chinese Journal of Animal Nutrition, 2025, 37(02):1325-1339.
[8]Liu Yisa. LC-MS based metabonomics study on the lung moistening and cough relieving effect of Momordica grosvenorii[D]. Guilin Medical University, 2022. DOI:10.27806/d.cnki.gglyx.2022.000213.