Salvia Miltiorrhiza Extract Powder

Salvia Miltiorrhiza Extract Powder

Specification: tanshinone IIA 0.5%
Appearance: Brown red powder
Plant Part: Root
Application: Medical, Health care, Food

Annual Supply Capacity: 20MT
Package: 25KG/Fiber Drum, Foil Bag
Storage: Keep dry and cool
Shelf Life: 24 Months
Botanical Source: Amomum villosum Lour

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Description
Technical Parameters

What is Salvia Miltiorrhiza Extract Powder?

When it comes to natural health supplements, there are few that have gained as much attention as Salvia Miltiorrhiza Extract Powder. This potent extract has been used in traditional Chinese medicine for centuries and is now becoming increasingly popular around the world. Salvia Miltiorrhiza, also known as Dan Shen, is a perennial herb that grows in Asia. The root of the plant has been used for centuries in traditional Chinese medicine to treat a variety of conditions, including cardiovascular disease, neurological disorders, and inflammation. The extract is made by grinding the dried root into a fine powder and extracting the active compounds using a proprietary process.

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Salvia Miltiorrhiza extract is a brown-red powdery product extracted from the dried roots and rhizomes of Salvia Miltiorrhiza. It contains many active substances, such as tanshinone and tanshinone and is also rich in vitamin A and trace elements such as iron and potassium. It has a wide range of applications, not only in skin care, such as improving acne skin, but also in other areas.

Specification:(Purity)
Tanshinone IIA 0.5%
Salvianolic acid B 1.2%
Detection method:
It is in accordance with the determination method of tanshinone IIA and salvianolic acid B in Salvia Miltiorrhiza, the first part of "Pharmacopoeia of the People's Republic of China". Refer to corporate standards Q/XATM 024-2018 and Q/XATM 010-2018.

 

Certificates of Analysis (COA)

Product Name

Salvia Miltiorrhiza Extract Powder

Batch Size

500 kg

CAS No.

N/A

Batch No.

AP20240813

MFG. Date

Aug. 13, 2024

Retest Date

Aug. 12, 2026

Issue Date

Aug. 20, 2024

Retest Date

Aug. 12, 2026

ITEM

SPECIFICATION

RESULT

TEST METHOD

Physical Description

Appearance

Brown Powder

Conforms

Visual

Odor

Characteristic

Conforms

Organoleptic

Taste

Characteristic

Conforms

Olfactory

Particle size

95% passes through an 80 mesh sieve

Conforms

CP2015

Chemical Tests

Assay

tanshinone IIA 0.5% Conforms

HPLC

Loss on drying

≤3.0%

2.45%

CP2020 (105 oC, 3 h)

Ash

≤5.0%

2.17%

CP2020 (600 oC, 4 h)

Heavy Metals

≤2 ppm

Conforms

CP2020

Lead (Pb)

≤0.2 ppm

Conforms

CP2020(AAS)

Arsenic (As)

≤0.1 ppm

Conforms

CP2020(AAS)

Cadmium (Cd)

≤0.1 ppm

Conforms

CP2020(AAS)

Mercury (Hg)

≤0.1 ppm

Conforms

CP2020(AAS)

Microbiology Control

Aerobic bacterial count

≤1,000 cfu/g

Conforms

CP2020

Total Yeast & Mold

≤100 cfu/g

Conforms

CP2020

Escherichia coli.

Negative

Conforms

CP2020

Salmonella

Negative

Conforms

CP2020

Conclusion

Conforms to specification

Storage

Store in tightly sealed, preferably full containers, in a cool, dry, and well-ventilated area.

Shelf Life

24 months when properly stored.

Status

Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified.

 

Is Salvia Miltiorrhiza Extract Powder Effective? How Does It Work?

Salvia miltiorrhiza extract has a variety of efficacy and effects. First, from a medicinal point of view, it can effectively reduce endothelial damage, especially in patients with acute stroke or pulmonary embolism, atherosclerosis, or diabetes can promote endothelial repair. In addition, it also has excellent anti-inflammatory effects and has many clinical applications, especially for arthritis and viral myocarditis.

1. Cardiovascular Health
Danshensu, salvianolic acid B, and other water-soluble components can relax vascular smooth muscle through various mechanisms. They can promote the release of nitric oxide (NO) from endothelial cells, which is a potent vasodilator that can activate guanylate cyclase, reduce intracellular calcium ion concentration, thereby causing vasodilation, increasing organ blood flow, and improving microcirculation disorders.[4]

 

2. Cognitive Function
Danshen extract can improve blood supply to the brain by dilating cerebral blood vessels and inhibiting platelet aggregation. Meanwhile, its antioxidant and anti-inflammatory effects can effectively resist the damage of neurons caused by oxidative stress and inflammation. Some studies also suggest that tanshinone IIA may inhibit the aggregation and toxicity of β-amyloid protein, which is of great significance for the prevention and treatment of neurodegenerative diseases such as Alzheimer's disease.

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3. Inflammation
Both tanshinone and phenolic acid exhibit significant anti-inflammatory activity. They can inhibit key pro-inflammatory signaling pathways, such as nuclear factor kappa B (NF-κB) and mitogen activated protein kinase (MAPK) pathways, thereby downregulating the expression and release of various pro-inflammatory cytokines, such as tumor necrosis factor alpha (TNF - α), interleukin-6 (IL-6), and interleukin-1 β (IL-1 β), fundamentally inhibiting the "cascade amplification effect" of inflammatory responses.[4]


4. Skin Health
Salvia Miltiorrhiza Extract Powder is rich in phenolic compounds such as salvianolic acid B and danshensu, which are natural and potent antioxidants. Its molecular structure contains a large number of phenolic hydroxyl groups, which can provide hydrogen atoms and directly neutralize excess free radicals (such as superoxide anions, hydroxyl radicals, etc.) in the body, converting them into stable and harmless substances.

 

What Are the Applications of Salvia Miltiorrhiza Extract Powder?

  • Capsules: This is the most common form of dietary supplement. Salvia Miltiorrhiza Extract Powder can be precisely filled into hard or soft capsules. The capsule form can effectively mask the unpleasant odor of the raw materials, facilitate swallowing, and effectively protect the contents from the effects of light and moisture, ensuring the stability of the ingredients.
  • Tablets: Tablets are made by mixing with excipients to form tablets that are easy to carry and take. It can be designed in various forms, such as instant tablets, chewable tablets, or effervescent tablets, to meet the preferences of different consumers. The automation level of tablet production is high, and the cost is relatively low.

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  • Powder/granule: Mix Salvia Miltiorrhiza Extract Powder directly with other functional ingredients (such as probiotics, fruit powder, etc.), or package it separately into small bags, making it convenient for consumers to rinse and drink directly or add it to milk, yogurt, juice, smoothies, etc. This form absorbs quickly, may have higher bioavailability, and has a flexible formula, making it particularly suitable for children, people with swallowing difficulties, and consumers who enjoy DIY healthy drinks.
  • Functional foods and beverages: Salvia Miltiorrhiza Extract Powder can be used as a functional ingredient and added to a wider range of food systems. For example, developing health teas with cardiovascular health claims, energy bars, breakfast cereals, functional oral liquids, etc. This greatly expands its consumption scenarios, making health supplements more routine and food-based.

 

Why Appchem?

Our Salvia Miltiorrhiza Extract Powder is 100% pure and contains no fillers or additives. We use only the highest quality root, which is grown and harvested under strict conditions to ensure maximum potency and purity. Our extract is standardized to contain a minimum of 50% salvianolic acid B and rosmarinic acid, the two primary active compounds found in the plant.

Salvia Miltiorrhiza Extract Powder

Salvia Miltiorrhiza Extract Powder is a potent and effective natural health supplement that offers a range of potential benefits. We are committed to providing our customers with the highest quality product possible and are proud to offer our Salvia Miltiorrhiza Extract Powder at an affordable price. Whether you are a health food store owner, an online retailer, or any other type of merchant, we believe that our product has the potential to be a valuable addition to your lineup.

 

Certificates

certificates

Security statement:

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company. 

 

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Qualification

 

Production Base

XI'AN APP-CHEM BIO (TECH) CO., LTD.
Bon Natural Life(Nasdaq: BON)

The Company is headquartered in Xi'an High-tech Zone, Shaanxi Province, with an independent R&D center and testing laboratories. Its Dali and Tongchuan production sites cover a total area of nearly 20,000 square meters, and it operates through the marketing networks in and out of China.

DALI FACTORY

  • Covering 30 acres and a building area of 11000 m²
  • Having a plant extract workshop, a precision drying and packaging workshop, and a spice refining workshop

TONGCHUAN FACTORY

  • Covering 20 acres, with a construction area of 6900 m²
  • Having 3 clean workshops, 2 formula product production lines, and 1 special food production line under construction.
-2000-2000

2006

Foundation

17,900 m²

Building area

90M

Order received

30+

Patents

 

Reference
[1]T. Cheng. "Cardiovascular effects of Danshen." International journal of cardiology (2007). [2007-09-14]
[2]Jing‐Yan Han, Jing-yu Fan et al. "Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion." Pharmacology & therapeutics (2008). [2008-02-01]
[3]Limin Zhou, Z. Zuo et al. "Danshen: An Overview of Its Chemistry, Pharmacology, Pharmacokinetics, and Clinical Use." The Journal of Clinical Pharmacology (2005). [2005-12-01]
[4]Research progress on the pharmacological mechanism and application of Danshensu and its derivatives. [2021-02-01]

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