Pure Naringin Powder

Pure Naringin Powder

Specification: (Purity)98%
CAS number: 10236-47-2
Appearance: Off-white Powder
Application: Medical, health care, food, Cosmetics

Annual Supply Capacity: 20MT
Package: 25KG/Fiber Drum, Foil Bag
Shelf Life: 2 Years, storage in a ventilated, low-temperature, and dry place
Botanical Source: Citrus grandis L.

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Description
Technical Parameters

1. What is Naringin Powder?

Natural naringin powder is a natural flavonoid compound extracted from the peel of citrus plants in the Rutaceae family, especially grapefruit, grapefruit, and orange. As a key phytochemical, naringin endows citrus fruits with a unique bitter taste and is also an important secondary metabolite for plants to resist external environmental stress. In nature, it exists in the form of glycosides, formed by the connection of its glycoside-naringin with a new orange peel sugar (disaccharide) through glycosidic bonds.
The biological activity research of naringin has a long history. In traditional medicine, citrus peels containing naringin are often used for regulating qi, resolving phlegm, improving digestion, and strengthening the spleen. Modern scientific research has systematically revealed its extensive pharmacological activities through in vitro cell experiments and in vivo animal models, elevating it from a traditional herbal ingredient to a new star of modern dietary supplements with clear scientific endorsement.

 

Melting point: 171-174ºC

Naringin_[10236-47-2]_296×150_3D_Conformer

Molecular formula: C27H32O14

Molecular weight: 580.53

EINECS/ELINCS Registration Number: 233-566-4

Structural formula:

 

2. Certificate Of Analysis (COA)

Product Name

Naringin

Botanical Source

Citrus grandis L.

CAS No.

10236-47-2

Plant Part

Fruit

ITEM

SPECIFICATION

RESULT

TEST METHOD

Physical Description

Appearance

Off-white powder

Conforms

Visual

Odor

Characteristic

Conforms

Organoleptic

Taste

Characteristic

Conforms

Olfactory

Particle size

95% passes through an 80 mesh sieve

Conforms

CP2020

Chemical Tests

Assay(on dry basis)

≥98.0%

98.07%

HPLC

Loss on drying

≤5.0%

3.83%

CP2020 (105 oC, 3 h)

Ash

≤1.0 %

0.15%

CP2020 (600 oC, 4 h)

Heavy Metals

≤10 ppm

Conforms

CP2020

Lead (Pb)

≤2 ppm

Conforms

CP2020(AAS)

Arsenic (As)

≤2 ppm

Conforms

CP2020(AAS)

Cadmium (Cd)

≤1 ppm

Conforms

CP2020(AAS)

Mercury (Hg)

≤1 ppm

Conforms

CP2020(AAS)

Microbiology Control

Aerobic bacterial count

≤1,000 CFU/g

Conforms

CP2020

Total Yeast & Mold

≤100 CFU/g

Conforms

CP2020

Escherichia coli

Negative

Conforms

CP2020

Salmonella

Negative

Conforms

CP2020

Conclusion

Conforms to specification

Storage:

Store in tightly sealed and preferably full containers in a cool, dry, and ventilated area.

Shelf Life

24 months when properly stored.

Status:

Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified.

 

3. What is the Process Flow Diagram?

 

Get the pomelo peel, and remove the pulp and stem.

Cut the pomelo peel into small pieces, wash and dry.

Grind the dried pomelo peel into powder.

Add an appropriate amount of emulsifier and rheological agent to Naringin powder.

Dry the mixture in a high-efficiency spray dryer.

Adjust the particle size and density of the powder as needed.

Carry out packaging and packaging, and store in a dry and cool place.

The production process ensures the purity and quality of Naringin powder, which meets the relevant standards of food and medicine.

 

4. Is Naringin Powder Effective? How Does It Work?

The core value of natural naringin powder as a dietary supplement stems from its diverse health benefits that have been validated through extensive scientific research. Its mechanism of action is complex and intricate, usually through the synergistic action of multiple targets and pathways, regulating the physiological and biochemical balance within the body.

1. Strong antioxidant effects:

The molecular structure of naringin contains multiple phenolic hydroxyl groups, which can directly provide hydrogen atoms, effectively eliminate harmful free radicals such as superoxide anions and hydroxyl radicals, interrupt free radical chain reactions, and protect cell membranes, proteins, and DNA from oxidative damage.[1] At the same time, naringin can upregulate the activity and expression of endogenous antioxidant enzyme systems in the body, such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH Px), enhancing its own antioxidant defense ability.

2. Promote bone health and prevent osteoporosis:

Naringin can stimulate the differentiation of bone marrow mesenchymal stem cells (BMSCs) into osteoblasts and promote the proliferation, maturation, and mineralization functions of osteoblasts. Its mechanism of action involves activating multiple key osteogenic signaling pathways, including Wnt/β - catenin pathway, BMP/Smad pathway, and PI3K/Akt pathway.[2] The activation of these pathways upregulates the expression of key osteogenic transcription factors such as Runx2 and Osx, thereby increasing the synthesis of bone matrix such as type I collagen and osteocalcin.

3. Cardiovascular protective effect:

Naringin can regulate lipid metabolism, reduce the levels of serum total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C), and increase the level of high-density lipoprotein cholesterol (HDL-C) to prevent the formation and development of atherosclerosis.[1] In addition, it also has potential benefits such as antiplatelet aggregation and antiarrhythmic effects.

 
Benefits of Naringin
 

Its mechanism of action is complex and intricate, usually through the synergistic action of multiple targets and pathways

ROS-496-372
Strong antioxidant effects
-496-372
Promote bone health
-496-372
Cardiovascular protective effect

 

5. Precautions for use

 

98

Naringin powder is suitable for anyone who needs its health benefits, especially those who want to improve digestion, boost the immune system, lower cholesterol, and promote cardiovascular health.

 

However, a doctor should be consulted before use to ensure suitability for one's medical condition.

 

Also, pregnant and breastfeeding women and people who are taking medications should avoid naringin powder.

The recommended dosage of naringin powder is 100-500 mg per day, which can be taken 2-3 times. Best taken before or within 30 minutes of a meal. Before use, read the product label or consult a physician for the most accurate dosage and usage information. It is best to use pomelo peel powder with a healthy diet, eat small meals often, and eat a healthy and comprehensive diet. High-sugar, high-fat, and high-salt foods should be avoided while maintaining moderate exercise and adequate water intake. Please note that pomelo peel powder is only an auxiliary health product and cannot replace normal medical treatment and treatment. If you have any medical concerns, please consult your physician for professional advice. In the meantime, if you experience any side effects or discomfort, discontinue use and seek medical attention as soon as possible.

 

6. What Are the Applications of Naringin Powder?

★ Nutritional Supplements – Pomelo peel powder is often added to nutritional supplements, such as vitamin formulas or pre-workout supplements. It is thought to aid in weight loss, regulate blood sugar levels, and reduce inflammation.

★ Skincare: Naringin Powder has the functions of anti-oxidation, anti-inflammation, and enhancing skin luster. Therefore, it is widely used in skincare products, especially to prevent skin damage caused by solar radiation. Studies have shown that using skin care products containing Naringin Powder can reduce skin pigmentation and improve skin clarity. Some creams, masks, and other products contain Naringin Powder.

★ Hair care products – Naringin powder is known to help promote hair growth and stimulate hair follicles, making it a popular ingredient in hair care products like shampoos and conditioners.

★ Food and Beverages - Pomelo peel powder is often used as a flavoring agent in the food and beverage industry, especially in lemon and citrus-flavored beverages. Overall, naringin powder is widely used in various industries for its potential health benefits and as a natural ingredient in various products.

★ Oral care: Naringin Powder can effectively inhibit the growth of oral bacteria, reduce oral odor, and bad breath. Therefore, it is widely used in oral cleaning products and oral disinfectants. For example, some toothpaste, mouthwash, and other products contain Naringin Powder. At the same time, Naringin Powder also has the effect of promoting dental health. Studies have found that mouthwashes containing Naringin Powder can reduce oral problems such as bleeding gums and periodontitis.

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7. Certificates

certificates

Security statement:

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.

Tags: Naringin Powder, Naringin manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk

 

Qualification

Reference
[1] Research progress on pharmacological effects and mechanisms of naringin, Yang Xinrong et al. [2022-05]
[2] The molecular mechanism of naringin in preventing and treating osteoporosis, Wang Wenchi et al.[2024-12]
[3] Rui-Qin Chen, Qiaochu Qi et al. "Therapeutic potential of naringin: an overview." Pharmaceutical Biology (2016). [2016-08-26]
[4] Xuan Zeng, Weiwei Su et al. "Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Naringin in Aged Rats." Frontiers in Pharmacology (2019). [2019-01-28]

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