Quercetin Dihydrate Powder

Quercetin Dihydrate Powder is a natural flavonoid compound derived from various plants such as onions, apples, and grapes, representing one of the most prevalent antioxidant constituents in botanicals. Owing to its pronounced effects in antioxidant defence, anti-inflammatory action, immune support, and cardiovascular health, it is extensively utilised in dietary supplements and functional health products, establishing itself as a botanical active ingredient with clearly defined functional applications.

Unlike conventional quercetin extracts, Quercetin Dihydrate Powder employs a standardised extraction process that preserves the compound in its dihydrate form. This structure exhibits superior water solubility and stability. APPCHEM utilises precise solvent extraction and separation techniques to ensure maximum retention of quercetin's purity and bioactive components. This process not only achieves ideal enrichment of the active ingredient but also guarantees consistent batch-to-batch stability.

Quercetin Dihydrate Powder typically presents as a yellow to pale yellow powder, exhibiting excellent water solubility and formulation compatibility. It is suitable for various dosage forms, including capsules, tablets, granules, instant powders, and functional beverages. In practical applications, quercetin dihydrate powder frequently serves as a core ingredient in functional formulations targeting antioxidant, immune support, and anti-inflammatory benefits. It finds extensive use particularly in cardiovascular health products, sports recovery supplements, and seasonal wellness formulations. It may also be synergistically combined with other antioxidant components-such as vitamin C, green tea extract, and grape seed extract-to enhance the overall efficacy of the product.

XI'AN APP-CHEM BIO (TECH) CO., LTD. (APPCHEM) provides Quercetin Dihydrate Powder utilising a mature, reproducible industrial plant extraction process, comprising the following principal steps:

1. Washing
2. Filtering
3. Removing impurities
4. Drying: to prevent high-temperature damage to thermosensitive active ingredients, especially volatile oils.
5. Crushing: (such as 80 mesh) to increase the contact area with the solvent and improve extraction efficiency.
6. Extraction
7. Solid-liquid separation
8. Purification
9. Concentrate
10. Drying
11. Smashing
12. Packaging
13. Finished product

The health benefits of quercetin dihydrate are rooted in its potent multi-targeted biological activity. Extensive in vitro studies, animal experiments, and a growing body of human clinical trials have confirmed its efficacy across multiple health domains. Its mechanism of action is complex and synergistic, primarily centred on its antioxidant, anti-inflammatory, and signalling pathway regulatory capabilities.

• Potent Antioxidant Activity

Quercetin dihydrate ranks among nature's most potent antioxidants. It effectively neutralises excess free radicals within the body, shielding cell membranes, proteins, and DNA from oxidative damage. This protective action helps delay the ageing process, maintain normal organ and tissue function, and reduce the risk of numerous chronic diseases associated with oxidative stress. Its molecular structure contains multiple phenolic hydroxyl groups, which act as hydrogen donors. These groups react directly with free radicals such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), reducing them to harmless or less reactive compounds and thereby terminating chain reactions. Furthermore, quercetin dihydrate enhances the body's intrinsic antioxidant defences by activating the Nrf2 (nuclear factor E2-related factor 2) signalling pathway, thereby upregulating the expression of multiple endogenous antioxidant enzymes (such as heme oxygenase-1 and glutathione S-transferase).

• Significant Anti-inflammatory Activity

Supplementation with quercetin dihydrate markedly reduces plasma levels of inflammatory markers, including C-reactive protein (CRP), tumour necrosis factor-α (TNF-α), and interleukin-6 (IL-6). Quercetin dihydrate not only inhibits activation of the NF-κB (nuclear factor κB) signalling pathway in immune cells such as macrophages, but also inhibits the activity of cyclooxygenase (COX) and lipoxygenase (LOX), key enzymes in the arachidonic acid metabolic pathway whose products (such as prostaglandins and leukotrienes) are important inflammatory mediators.

• Cardiovascular System Protection

Cardiovascular health represents one of the most extensively researched and well-documented domains for quercetin dihydrate. Through its antioxidant and anti-inflammatory actions, quercetin dihydrate aids in protecting vascular endothelial cells, improving vasodilatory function, and inhibiting the formation process of atherosclerotic plaques. It promotes vasodilation by enhancing nitric oxide (NO) bioavailability and delays atherosclerotic progression by inhibiting the proliferation and migration of vascular smooth muscle cells. Its lipid-regulating effects may relate to its influence on the activity of enzymes involved in hepatic lipid metabolism.

With its exceptional scientific backing and versatility, quercetin dihydrate powder has become a highly favoured core ingredient within the dietary supplement and functional food industries. Its applications align closely with the market positioning of "premium multifunctional bioflavonoids" outlined in Part One, enabling brands to develop innovative products that address precise health requirements.

Core Application Areas

• Cardiovascular Health Supplements: This represents the primary application market. It serves as a core ingredient in capsules, tablets, or functional beverages designed to lower blood pressure, regulate lipid profiles, and maintain vascular health. It may be synergistically formulated with other cardio-protective components such as Coenzyme Q10, Omega-3 fatty acids, and garlic extracts.
• Immune Support and Anti-Allergy Products: Given its potent anti-inflammatory properties and mast cell-stabilising effects, quercetin is an ideal choice for developing seasonal support, allergy relief, and immune balance products. It is frequently combined with ingredients like vitamin C, zinc, and bromelain to enhance synergistic effects.
• Sports Nutrition and Recovery: Quercetin's anti-inflammatory and antioxidant properties aid in mitigating muscle damage and inflammatory responses triggered by intense exercise, accelerating physical recovery. Consequently, it is extensively utilised in pre-workout and post-workout recovery powder formulations, as well as daily supplements for endurance athletes.
• Healthy Ageing and Antioxidant Formulations: As a broad-spectrum antioxidant, quercetin serves as a cornerstone ingredient in anti-ageing and cellular health products. It can be incorporated into composite antioxidant formulations, synergising with other plant polyphenols (such as resveratrol and EGCG) and vitamins (like vitamin E) to deliver comprehensive cellular protection.
• Functional Foods and Beverages: With growing consumer demand for functional foods, quercetin dihydrate powder is increasingly incorporated into functional beverages, nutrition bars, cereal products, and gummies due to its excellent stability and processing adaptability, conferring additional health benefits to mass-market consumer goods.

Mainstream Product Forms

Within the B2B raw materials market, powder represents the predominant and most favoured product form for quercetin dihydrate, commanding the largest market share. Core advantages of the powder form include:

1. High formulation flexibility
2. Superior stability and shelf life
3. Cost-effectiveness and processing convenience
4. Potential for high bioavailability

Security statement：

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.

Hot Tags: quercetin dihydrate powder manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk.

Long-term cooperative logistics companies include international logistics companies such as DHL, FedEx, UPS, etc.

The regular bulk packaging of the product is a 25kg plastic bag and a cardboard drum. The sample is packaged in an inner aluminium foil bag and an outer plastic bag, supporting customised packaging solutions.

XI'AN APP-CHEM BIO (TECH) CO., LTD. (APPCHEM) regularly participates in international raw material exhibitions such as CPHI, SSW, and In Cosmetics Asia, and establishes long-term cooperative relationships with global customers.

Q1. How is the purity of this product verified?
A1: We employ authoritative analytical methods such as High Performance Liquid Chromatography (HPLC) and Ultraviolet Spectroscopy (UV) to ensure a content of 95%.

Q2. What is the minimum order quantity for Quercetin Dihydrate Powder?
A2: Our minimum order quantity (MOQ) varies by product and specific requirements, and is typically negotiable. Please contact us for detailed information.

Q3. What is the delivery timeframe for the product?
A3: Delivery times depend on order volume and product type. Generally, we arrange production and dispatch promptly upon order confirmation.

Q4. Does APPCHEM offer customisation services?
A4: Yes, we provide customisation services including packaging, labelling, and adjusting product specifications to meet specific client requirements.

Q5. How does APPCHEM ensure product quality and stability?
A5: We maintain a rigorous quality control system. All products undergo third-party testing, with detailed COA (Certificate of Analysis) and stability data provided.

Q6. Do your products comply with international regulatory requirements?
A6: Yes, our products meet quality certification standards such as ISO. We can supply all necessary export compliance documentation, including Certificates of Origin and quality inspection reports.

Reference
[1]Yao Li, Jiaying Yao et al. "Quercetin, Inflammation and Immunity." Nutrients (2016).
[2]O. Shuvalov, Yulia Kirdeeva et al. "Phytochemicals Target Multiple Metabolic Pathways in Cancer." Antioxidants (2023).
[3]P. Bellavite. "Neuroprotective Potentials of Flavonoids: Experimental Studies and Mechanisms of Action." Antioxidants (2023).
[4]S. Egert, S. Wolffram et al. "Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans." The Journal of Nutrition (2008).
[5]Susanne Andres, S. Pevny et al. "Safety Aspects of the Use of Quercetin as a Dietary Supplement." Molecular Nutrition & Food Research (2018).
[6]R. Edwards, Tiffany Lyon et al. "Quercetin reduces blood pressure in hypertensive subjects." The Journal of Nutrition (2007).
[7]M. Harwood, B. Danielewska-Nikiel et al. "A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties." Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association (2007).