Flos Chrysanthemi Extract

The medicinal history of chrysanthemum (Chrysanthemum morifolium Ramat.) can be traced back over two thousand years, and it is one of the most well-known and widely used medicinal and edible plants in traditional Chinese medicine. In the theoretical system of traditional Chinese medicine, chrysanthemum has a sweet and bitter taste, a slight coldness, and belongs to the lung and liver meridians. This unique characteristic determines its core pharmacological action direction.

The chrysanthemum extract provided by APPCHEM does not simply mix chrysanthemums from different sources, but establishes a strict raw material screening system. We select high-quality chrysanthemums from authentic medicinal regions that meet the requirements of the Pharmacopoeia of the People's Republic of China, ensuring the purity and efficiency of the raw materials from the source. Through modern analytical techniques, we conduct active ingredient fingerprint analysis on different batches of raw materials to ensure that their chemical patterns are highly consistent with traditional high-quality medicinal materials, thereby ensuring the stability and predictability of the extract's efficacy.

Modern plant chemistry research has revealed the material basis behind the efficacy of chrysanthemums.
Its main active ingredients include

1. flavonoids (such as verbascoside, apigenin glycoside, acacetin, etc.)
2. organic acids (such as chlorogenic acid, caffeic acid, 3,5-O-dicaffeoylquinic acid, etc.)
3. volatile oils
4. polysaccharides

Among them, flavonoids and phenolic acids such as verbascoside and chlorogenic acid are widely regarded as key substances that exert pharmacological activities such as anti-inflammatory, antioxidant, antibacterial, and antihypertensive effects.

Our chrysanthemum extract uses standardised production processes to quantitatively control these indicator components, making it not only a concentration of traditional chrysanthemums but also a modern Chinese medicine raw material with clear functional substances and controllable quality standards. 

Modern science has revealed the biological mechanisms behind the traditional efficacy of chrysanthemums at the molecular level through extensive experimental research.

Anti-inflammatory and immune regulatory effects:

This is the core mechanism of chrysanthemum's "dispersing wind heat" and "clearing heat and detoxifying" effects. Research has confirmed that flavonoids such as verbascoside and apigenin in chrysanthemum extract can significantly inhibit the production of various inflammatory mediators such as nitric oxide (NO), prostaglandin E2 (PGE2), tumour necrosis factor-α and interleukin-6 (IL-6) in macrophages induced by lipopolysaccharide (LPS). Its mechanism of action involves inhibiting the activation of key inflammatory signalling pathways such as NF-κB and MAPK. This multi-target anti-inflammatory effect explains why it can effectively alleviate inflammatory reactions such as fever, sore throat, and redness.

The protective effect on the cardiovascular system:

The efficacy of chrysanthemum in "calming the liver" is closely related to cardiovascular protection. The components, such as chlorogenic acid and 3,5-O-dicaffeoylquinic acid in its extract, have been proven to have vasodilatory and hypotensive effects. The mechanism may be related to promoting the release of nitric oxide (NO) from endothelial cells and inhibiting the activity of angiotensin-converting enzyme (ACE). In addition, its powerful antioxidant capacity can eliminate free radicals, reduce the oxidation of low-density lipoprotein (LDL), inhibit the formation of atherosclerotic plaque, and thus play a comprehensive role in protecting the cardiovascular system.

Broad-spectrum antibacterial and antiviral effects:

The "clearing heat and detoxifying" effect of chrysanthemums is closely related to their ability to directly inhibit pathogenic microorganisms. In vitro studies have shown that chrysanthemum extract has varying degrees of inhibitory effects on various bacteria, such as Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, as well as influenza virus, herpes simplex virus, etc. This provides direct pharmacological evidence for its application in the treatment of infectious diseases.

In summary, chrysanthemum extract achieves a perfect unity of traditional efficacy and modern pharmacology through the synergistic effects of multiple components, targets, and pathways, making it a modern Chinese medicine raw material with clear efficacy, mechanism, and reliable quality.

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Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.

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	Proven Expertise & Global Reach Nasdaq-listed(Nasdaq: BON) manufacturer with 19+ years in herbal extract production and 19+ years of export experience; Products are distributed to over 100 countries, and extensive participation in international exhibitions.
	24/7 Customer-Centric Service Dedicated 4-person after-sales team providing real-time support; Comprehensive order tracking system for full supply chain visibility.
	Certifications & Industry Leadership 20+ certifications: China SC License, ISO9001/ISO22000, FDA, Kosher, Halal, etc.; Passed FDA unannounced inspections and on-site audits by global authorities; 30+ national patents, 53 registered trademarks; drafted 4 international standards (e.g., Stachyose, Apple Extract); Established enterprise standards for Sclareol/Ambroxide, enabling premium market access.
	End-to-End Quality Control Raw Material Selection: Procurement with full traceability; Advanced Production: 100,000-Class cleanrooms, triple-core technologies (ton-scale extraction, heavy metal removal, enzymatic purification) meeting FDA/EU standards; Rigorous Testing: The QC department conducts strict inspections from raw materials to finished products.
	R&D & Customisation Capabilities PhD-led R&D team (>50% hold advanced degrees) with cutting-edge equipment (e.g., molecular distillation, nanofiltration); Custom formulations, packaging, and OEM solutions; factory audits accepted; no trader involvement.
	Robust Supply Chain High Capacity: 50+ technicians, multiple production lines, daily output exceeding 1,000 tons; Fast Delivery: 80% of orders are shipped immediately; global logistics network (EU/US) with door-to-door multimodal transport; Inventory Efficiency: 40+ SKUs across 4 product lines, 1,000+ tons of inventory for flexible fulfilment.
	Competitive Cost Structure Factory-direct pricing reduces procurement and logistics costs. Partnerships with packaging and logistics providers ensure cost-effective solutions.
	Cutting-Edge Testing Lab Equipped with HPLC, atomic absorption spectrometers, UV spectrophotometers, etc. Full-spectrum testing for heavy metals, microorganisms, and compliance with global regulations.

Reference

[1]A KVIK KARI KÖNYVTÁR 2018. FEBRUÁRI FOLYÓIRATCIKK GYARAPODÁSA SZAKTERÜLET SZERINT. Tóth Réka Anna. [2018-01-02]

[2]Flos Chrysanthemi indici essential oil: Comparative study of extraction methods on yield and biological activities. Not specified in the provided text.

[2019-09-21]

[3]The exposure of luteolin is much lower than that of apigenin in oral administration of Flos Chrysanthemi extract to rats. [2012-09-01]

[4]Q. Jia, Xuhua Huang et al. "Pharmacokinetic Study of Thirteen Ingredients after the Oral Administration of Flos Chrysanthemi Extract in Rats by UPLC-MS/MS." BioMed Research International (2020). [2020-08-21]

[5]Formulation and Test of Antioxidant Activity from Serum Gel of the Extract of Chrysanthemum Flower (Chrysanthemum Indicum L.). Shelly Taurhesia et al. [2024-02-29]