Horny Goat Weed Extract Supplier

Horny Goat Weed Extract Supplier

Specification: (Purity)Icariin
CAS number: 476-66-4
Appearance: Brown powder
Application: Medical, Health care, Food, Cosmetics

Annual Supply Capacity: 20MT
Packing: 25KG/Fiber Drum, Foil bag
Storage: Keep dry and cool
Shelf Life: 24 Months
Botanical Name: Epimedium sagittatum

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Description
Technical Parameters

Horny Goat Weed, also known as Epimedium, is a plant that has been used for centuries in Traditional Chinese Medicine as an aphrodisiac to enhance libido, increase energy levels, and promote overall well-being. Herba epimedium extract is a brown powdery product extracted from the dried leaves of Epimedium sagittatum maxim, Epimedium pubescent. Horny Goat Weed is a natural source of icariin, an active compound that helps support healthy sexual function in both men and women.

 

1. What is Horny Goat Weed Powder?

In China, Epimedium has a history of medicinal use spanning over two millennia, first documented in the Shennong Ben Cao Jing (The Divine Farmer's Materia Medica). The English common name "Horny Goat Weed" originates from an ancient legend where a goat herder observed unusually heightened sexual activity in his flock after they grazed on the plant, thus discovering its potential aphrodisiac properties.

Melting point: 223-225 °C
Boiling point: 948.5±65.0°C
Molecular formula: C33H40O15
Molecular weight: 676.66

Structural formula:

product-269-158

 

2. Certificate Of Analysis (COA)

Product Name

Horny Goat Weed Powder Extract (Icariin)

Botanical Source

Epimedium Brevicornum

CAS No.

476-66-4

Plant Part

Leaf

ITEM

SPECIFICATION

RESULT

TEST METHOD

Physical Description

Appearance

Brown powder

Conforms

Visual

Mesh Size
95% pass 80 mesh

Conforms

CP2020

Taste

Characteristic

Conforms

Olfactory

Identification
(+)
Positive
TLC

Chemical Tests

Assay

≥10.0%

10.63%

HPLC

Loss on drying

≤5.0%

3.12%

CP2020 (65 ℃, 3h)

Ash

≤5.0%

0.59%

CP2020 (600℃, 4h)

Heavy Metals

≤10 ppm

<10 ppm

CP2020

Pb
≤2.0 mg/kg
Conforms
GB 5009.75
As
≤1.0 mg/kg
Conforms
GB 5009.76
Hg
≤0.3 mg/kg
Conforms
GB 5009.17
HCH
≤0.2 mg/kg
Conforms
GB 5009.19
DDT
≤0.2 mg/kg
Conforms
GB 5009.19

Microbiology Control

Aerobic bacterial count

≤1,000 CFU/g

<10 CFU/g

CP2020

Total Yeast & Mold

≤100 CFU/g

<10 CFU/g

CP2020

Escherichia coli

Negative

Conforms

CP2020

Salmonella

Negative

Conforms

CP2020

Conclusion

Conforms to specification

Storage:

Store in a cool, dry, well-ventilated area; keep in tightly sealed containers, preferably full.

Shelf Life:

24 months when properly stored.

Status:

Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified.

 

3. What is the Process Flow Diagram?

The production of Horny Goat Weed Extract follows a rigorous, standardized process designed to maximize the extraction and concentration of target active compounds (like icariin) while removing impurities and ensuring the safety and stability of the final product. This process typically includes raw material pre-treatment, extraction, filtration, concentration, purification, drying, and final product processing.[1]

3.1 Raw Material Reception and Pre-treatment:

The herbs are cleaned to remove dirt and other impurities, then dried. The dried material is fed into a pulverizer and crushed to a suitable particle size (e.g., 40-60 mesh).

3.2 Extraction:

Based on the polarity of the target compound, icariin (a flavonoid glycoside), water or an ethanol-water mixture is typically chosen as the extraction solvent. Ethanol effectively dissolves flavonoids, while water helps extract some water-soluble substances and adjust polarity.[2]

3.3 Filtration and Separation:

Perform solid-liquid separation on the merged extract to remove the drug residue and obtain a clear extract.[3] This step aims to remove insoluble macromolecules and plant fibers.

3.4 Concentration:

The clear extract is pumped into vacuum concentration equipment (e.g., single-effect or multi-effect evaporators, rotary evaporators). Under reduced pressure and lower temperatures (e.g., 50-60°C), most of the solvent is evaporated, producing a concentrated paste with a relative density of approximately 1.10–1.20.

3.5 Purification and Drying:

The purified eluate or concentrated paste is dried to obtain a stable powder. The most common method is spray drying. Vacuum drying is another option, which uses lower temperatures and is better suited for protecting heat-sensitive substances.

3.6 Final Product Processing:

The dried material is crushed and passed through a standard sieve (e.g., 80-100 mesh) to ensure uniform particle size.

product-537-579

 

4. Is Horny Goat Weed Extract Effective? How Does It Work?

The efficacy of Horny Goat Weed Extract is rooted in its long history of traditional use and has been validated by modern scientific research. Its core active ingredient, icariin, is the material basis for most of its pharmacological activities.

Efficacy and Mechanism of Action
CGMP-200-200
Improving Sexual Function and Erectile Dysfunction
Icariin is a natural and selective PDE5 inhibitor. Icariin increases the level of cGMP within the corpus cavernosum, thereby enhancing the NO signaling pathway, promoting smooth muscle relaxation, increasing blood flow, and ultimately inducing and sustaining an erection.
Its mechanism is similar to that of the well-known drug sildenafil, but its effects are generally milder with fewer side effects.[4]
-200-200
Bone Health and Anti-Osteoporosis
Icariin can mimic some effects of estrogen without its associated side effects. It can promote the proliferation and differentiation of osteoblasts and increase the synthesis of bone matrix proteins by activating estrogen receptors or upregulating the expression of BMPs.
Concurrently, it inhibits the differentiation and activity of osteoclasts, thus slowing bone loss and maintaining bone density.
-200-200
Neuroprotective Effects
Icariin can mitigate oxidative stress-induced damage to nerve cells, inhibit neuroinflammatory responses, reduce the production and neurotoxicity of beta-amyloid (Aβ) protein, and promote the proliferation and differentiation of neural stem cells, contributing to neural regeneration and repair.[5]
It also improves neuronal energy metabolism by modulating mitochondrial function.
TB-200-200
Immunomodulatory Effects
Both Epimedium polysaccharides and flavonoids are involved in immune regulation.
They can promote the proliferation of T and B lymphocytes, enhance the phagocytic function of macrophages, and increase the activity of natural killer (NK) cells, thereby strengthening both non-specific and specific immunity.[5]
 

 

5. What Are the Applications of Horny Goat Weed Extract?

Thanks to its diverse biological activities and well-defined efficacy, Horny Goat Weed Extract has become a favored ingredient in the global health industry with a wide range of applications.

5.1 Dietary Supplements:

This is the primary application market for the extract.

  • Men's Health Products: Formulations aimed at enhancing libido, improving erectile function, and boosting energy, often compounded with other natural ingredients like Maca, Tongkat Ali, and Yohimbine.
  • Bone Health Products: Targeted at middle-aged and elderly individuals, as well as postmenopausal women, for the prevention of osteoporosis. It is frequently combined with calcium, vitamin D, and vitamin K2.
  • Sports Nutrition: Due to its ability to promote nitric oxide production and improve blood flow, some pre-workout products include Horny Goat Weed Extract to enhance athletic performance and the "pump" sensation.
  • Anti-Aging and Cognitive Health: Its neuroprotective and antioxidant capabilities make it a key ingredient in supplements designed to support healthy aging, memory, and cognitive performance.

5.2 Functional Foods and Beverages:

The extract is added as a functional ingredient to health bars, functional drinks, men's health wines, or tea bags to impart additional health benefits to regular foods.

 
Applications
 
-496-372
Men's Health
-496-372
Bone Health
-496-372
Sports Nutrition
-493-372
Antiaging&Cognitive Health

5.3 Product Forms:

Horny Goat Weed Extract powder has good processing adaptability and can be made into various dosage forms, including:

  • Capsules/Tablets: The most common forms, offering accurate dosing and convenience.
  • Powders: Can be consumed directly with water or added to drinks and shakes.
  • Liquid Extracts/Tinctures: May offer faster absorption.
  • Gummies: An increasingly popular and more appealing supplement form.

 

 

6. Regulatory Compliance

The regulatory status of Horny Goat Weed Extract varies by country/region, with no uniform global standard.
In China, Epimedium is a legally recognized TCM herb. Its extract can be classified as a pharmaceutical ingredient, a health food ingredient, or a general food ingredient, depending on its intended use and registration pathway. The China Chamber of Commerce for Import & Export of Medicines & Health Products has issued group standards, such as T/CCCMHPIE 1.25-2018 Plant Extracts - Epimedium Extract, which provide a reference for quality control within the industry.

 

7. Why Choose APPCHEM?

Global Footprint, Local Expertise

Over half of our R&D team holds advanced degrees, driving cutting-edge developments in herbal extracts with 24/7 technical support in 30 + languages.

Our expertise in industrial-scale extraction produces high-quality, custom-tailored solutions that meet precise client requirements.

  • 30+certificate
    ISO 9001/22000 certified, FDA-compliant manufacturing across 2 facilities
  • 20+year
    Serving 972+ enterprises since 2006
-300-300
-300-3001 -300-3002

 

8. Certificates

certificates

Security statement:

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company. 

 

Tags: Horny Goat Weed Powder, Epimedium manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk.

 

Qualification

 

Reference:
[1] Explanation of the preparation of the national standard "Technical Specification for Plant Extract Production Process"
[2] Analysis of peony (Chinese paeoniflorin) in accordance with the 15th edition of the Japanese Pharmacopoeia. T. Fukaya.
[3] REPORT WITH THE MOST SUITABLE EXTRACTION CONDITIONS FOR OBTAINING THE PRESERVING COMPOUNDS FROM PUMPKIN BY-PRODUCTS
[4] The therapeutic effect and mechanism of icariin on vascular erectile dysfunction in rats, Yao Juncheng, et al. [2023-11]
[5] Research Progress on the Neuroprotective Mechanisms of Icariin: A Comprehensive Review, Song Yixiang, et al.
[6] Study on the Efficacy of Epimedium Extract Epimedium Saponins [2022-11-25]

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