What is Angelica Sinensis Extract Powder?
Angelica Sinensis Extract is a product extracted from the dried root of Angelica Sinensis. It is brown-yellow to brown powder in appearance, without impurities visible to the naked eye, and with a peculiar taste and odour.
Angelica sinensis (Oliv.) Diels, as a perennial herbaceous plant belonging to the Umbelliferae family, is known as the "female ginseng". Angelica sinensis extract is a standardized raw material product obtained by extracting, separating, and concentrating the core bioactive components from high-quality dried roots of Angelica sinensis using modern scientific technology. It provides safe, effective, and quality-controlled core ingredients for modern dietary supplements, functional foods, and personal care products.
Core Active Ingredients
Modern plant chemistry research has revealed the complex chemical composition system in Angelica sinensis extract. Its main active ingredients can be divided into the following categories:
- Phthalides: Ligustilide
- Organic acids and their esters: Ferulic acid, caffeic acid, coumaric acid, and other organic acids
- Polysaccharides: Angelica sinensis polysaccharides (ASPs)
- Other components: In addition, Angelica sinensis extract also contains flavonoids, amino acids, vitamins, and various trace elements.
These components work together to form the material basis of Angelica sinensis's pleiotropy.
Certificate Of Analysis (COA)
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Product Name |
Angelica Sinensis Extract | Latin Name | Angelica Sinensis |
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CAS No. |
/ |
Plant Part |
Root |
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ITEM |
SPECIFICATION |
RESULT |
TEST METHOD |
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Physical Description |
|||
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Appearance |
Brown-yellow powder |
Conforms |
Visual |
|
Mesh Size |
95％ pass 80 mesh |
Conforms |
CP2020 |
|
Taste |
Characteristic |
Conforms |
Olfactory |
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Chemical Tests |
|||
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Assay |
≥10.0% |
10.63% |
HPLC |
|
Loss on drying |
≤5.0% |
3.12% |
CP2020 (65 ℃, 3h) |
|
Ash |
≤5.0% |
0.59% |
CP2020 (600℃, 4h) |
|
Heavy Metals |
≤10 ppm |
<10 ppm |
CP2020 |
|
Pb |
≤2.0 mg/kg |
Conforms |
GB 5009.75 |
|
As |
≤1.0 mg/kg |
Conforms |
GB 5009.76 |
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Hg |
≤0.3 mg/kg |
Conforms |
GB 5009.17 |
|
Microbiology Control |
|||
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Aerobic bacterial count |
≤1,000 CFU/g |
<10 CFU/g |
CP2020 |
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Total Yeast & Mould |
≤100 CFU/g |
<10 CFU/g |
CP2020 |
|
Escherichia coli |
Negative |
Conforms |
CP2020 |
|
Salmonella |
Negative |
Conforms |
CP2020 |
|
Conclusion |
Conforms to specification |
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What is the Process Flow Diagram?
A scientific, rigorous, and optimized extraction process is key to ensuring efficient and specific extraction of target active ingredients from natural Angelica root, while removing ineffective or potentially harmful impurities.
1. Raw material selection and pretreatment
Selected high-quality Angelica sinensis from real estate areas such as Min County in Gansu Province. The selected Angelica roots were cleaned, impurities removed, sliced, and dried.
2. Core extraction and separation
Extraction is the core link of the entire process flow. We adopt targeted extraction techniques based on the physicochemical properties of the target active ingredient, such as polarity, solubility, and thermal stability.
3. Filtration and concentration
The extraction solution contains a large amount of drug residue and suspended impurities, which need to be clarified through multi-stage filtration to obtain a clear extraction solution. Subsequently, advanced concentration equipment was used to concentrate the extract.
4. Purification and refinement
To further improve product purity and target ingredient content, the concentrated solution will enter the purification stage.
5. Drying and Finished Products
The purified extract or solution is finally dried to produce a stable, easy-to-store, and transportable powdered product. We mainly use spray drying technology.
6. Quality Control and Packaging
Strict quality control points (QCP) have been established at every stage from raw materials to finished products.
Qualified products are sealed in double-layered sterile plastic bags and cardboard drums in the clean room (e.g., 25 kg/drum) to ensure stability and safety during the two-year shelf life.
Is Angelica Sinensis Extract Powder Effective?
As a powerful plant material, the extensive health benefits of Angelica sinensis extract are rooted in its complex chemical composition and multi-target biological mechanisms.
1. Guardians of female reproductive system health
- Bidirectional regulation of uterine smooth muscle
- Improve menstrual irregularities
2. Powerful blood and hematopoietic functions
- Proliferation of hematopoietic stem/progenitor cells:
- Improve hemoglobin and red blood cell levels:
3. Protective agents for the cardiovascular and cerebrovascular system
- Expand blood vessels and improve microcirculation
- Antiplatelet aggregation and antithrombotic formation:
4. Significant anti-inflammatory and immune regulatory effects
- Inhibition of inflammatory mediators:
- Bidirectional immune regulation:
5. Antioxidant and anti-aging effects
Diverse Product Forms
To meet the needs of different application scenarios and production processes, Angelica sinensis extract is available in various physical forms and specifications:
- Powder: This is the most mainstream product form. There are both those divided by extraction ratio (such as 10:1, 20:1) and those standardized by core active ingredient content (such as ligustilide ≥ 1%, ferulic acid ≥ 0.5%), the latter of which can better ensure the stability and repeatability of product efficacy.
- Capsules and Tablets: Standardized powders are directly filled into capsules or mixed with excipients and compressed into tablets. They are the most common finished form of dietary supplements, with precise dosage and convenient administration.
- Liquid Extract: It exists in the form of extracts, tinctures, or concentrates and can be directly used to prepare oral liquids, functional beverages, or as active additives in cosmetics.
- Granules: Easy to swallow, quickly absorbed, commonly used in traditional Chinese medicine formula granules or instant solid beverages.
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FAQ
Q: Is Angelica sinensis extract suitable for all women?
A: Not entirely. Although Angelica sinensis extract is very beneficial for most women, we do not recommend its use for pregnant and lactating women, as its regulatory effect on the uterus may have an impact on pregnancy. In addition, women with estrogen-sensitive diseases such as uterine fibroids and endometriosis, as well as women with bleeding tendencies (such as excessive menstruation) or taking anticoagulant drugs, should use them with caution after consulting a doctor or professional health consultant.
Q: Can men use Angelica sinensis extract?
A: Sure. Although Angelica sinensis is often referred to as a "women's supplement," many of its health benefits are universal for both men and women. For example, its powerful effects of nourishing blood and promoting blood circulation, improving cardiovascular health, anti-inflammatory, antioxidant, and enhancing immunity are also applicable to men. In traditional Chinese medicine theory, Angelica sinensis is also commonly used to treat various problems caused by male blood deficiency and blood stasis.
Q: What is the difference between Angelica sinensis extract and direct consumption of Angelica sinensis medicinal materials or powder?
A: 1. Standardization: Angelica sinensis extract undergoes modern technology, and the content of its core active ingredients (such as ferulic acid and ligustilide) is precisely measured and standardized.
2. Effectiveness: The extraction process concentrates the active substance, resulting in higher bioavailability and a much higher content of active ingredients per unit weight compared to the original medicinal material.
3. Convenience and safety: The extract is a fine powder that is easy to add to various dosage forms such as capsules, tablets, beverages, etc., making it convenient to take.
Q: Will taking Angelica sinensis extract cause internal heat?
A: Angelica sinensis has a warm nature. For people with a constitution that is too hot or has yin deficiency and excessive fire, if used alone or in excess, there may indeed be some symptoms of "excessive fire", such as dry mouth, sore throat, constipation, etc.
Q: How should the raw materials of Angelica sinensis extract be stored?
A: Angelica sinensis extract contains various active ingredients and is sensitive to light, heat, and moisture. To maintain its optimal quality and efficacy, it should be stored in a cool, dry, and dark environment, and the packaging should be well sealed to prevent moisture absorption, clumping, and oxidation.
Reference
[1]In vitro bioactive metabolite production and plant regeneration of medicinal plant Angelica sinensis. Tianmiao Huang. [2024-01-01]
[2]Research Progress in Pharmacological Effects and Mechanisms of Angelica sinensis against Cardiovascular and Cerebrovascular Diseases. Chen.
[2024-05-02]
[3]Extraction process optimization of volatile oil from fresh Ligusticum chuanxiong based on orthogonal design. LI Chao. [2020-06-28]
[4]Chunyan Hou, Mingsong Yin et al. "Recent progress in the research of Angelica sinensis (Oliv.) Diels polysaccharides: extraction, purification, structure and bioactivities." Chemical and Biological Technologies in Agriculture (2021). [2021-03-17]
