What is Polygoni Multiflori Preparata Extract?
Polygoni Multiflori Preparata, commonly known as Fo-Ti, is a traditional Chinese herb that is widely used in traditional Chinese medicine. It is a climbing vine native to China, with deep, knotted roots that have been used for centuries to promote longevity and vitality. Radix Polygonum Multiflorum Preparata extract is a brown powdery product extracted from the processed product of the dried root tubers of Polygonaceae Radix Polygonum Multiflorum Preparata.

Polygonum multiflorum extract is a traditional Chinese medicine preparation made from the dried tubers of Polygonum multiflorum Thunb, a plant in the Polygonaceae family, extracted with ethanol, concentrated, and dried. Its raw materials are mainly produced in southern Shaanxi, southern Gansu, eastern China, central China, southern China, Sichuan, Yunnan, and Guizhou. The active ingredients include stilbene glycoside, lecithin, emodin, and rhein. This extract has the effects of tonifying blood essence, black hair, strengthening bones and muscles, etc. It can inhibit atherosclerosis by regulating the level of blood lipids, and reduce the content of lipid peroxide in the liver and the levels of serum alanine aminotransferase and glutamic oxaloacetic transaminase, so as to reduce the damage of liver cells.
Certificate Of Analysis (COA)
|
Appearance |
Brown powder |
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Odor & Taste |
Characterisitic |
|
Loss on Drying |
≤5.0% |
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Ignition Residue |
≤0.5% |
|
Sieve Analysis |
≥80 mesh |
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Extract Solvent |
Ethanol |
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Total Plate Count |
<1000cfu/g |
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Total Yeast & Mould |
<100cfu/g |
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E.Coil |
Negative |
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Mites |
Negative |
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Salmonella |
Negative |
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Storage |
Store in tightly sealed and preferably full containers in a cool, dry, and ventilated area. |
What is the Process Flow Diagram?
Polygoni Multiflori Preparata Extract Powder is made from carefully selected roots, which are washed, sliced, cooked with black soybean, and dried. This process increases the potency of its active ingredients, which include stilbenes, anthraquinones, and flavonoids. These compounds have been found to have antioxidant, anti-inflammatory, neuroprotective, and immune-boosting properties, among others.
- Fresh fruits are washed.
- Filter
- Remove impurities
- Drying: to prevent high-temperature damage to thermosensitive active ingredients, especially volatile oils.
- Crushing: (such as 80 mesh) to increase the contact area with the solvent and improve extraction efficiency.
- Core extraction
- Solid-liquid separation
- Purification
- Concentrate
- Drying
- Smash
- Packaging
- Finished product
Is Polygoni Multiflori Preparata Extract Effective?
function of Polygonum multiflorum




- Antioxidant and anti-aging mechanisms:
This is the most well-known function of Polygonum multiflorum. Its core component, TSG, is a potent natural antioxidant. Research has shown that TSG can significantly eliminate free radicals in the body, upregulate the activity of endogenous antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH Px), and inhibit lipid peroxidation.
- Neuroprotective effect:
Polygonum multiflorum extract and its active ingredients have shown protective effects on various neurodegenerative disease models, such as Alzheimer's disease and Parkinson's disease. Its mechanism includes inhibiting neuroinflammation, reducing the production and toxicity of β-amyloid protein (Aβ), protecting dopaminergic neurons, promoting the proliferation and differentiation of neural stem cells, etc.
- Regulating lipid metabolism:
Polygonum multiflorum extract can effectively reduce serum total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C), while increasing high-density lipoprotein cholesterol (HDL-C). The mechanism may involve inhibiting the synthesis of cholesterol in the liver, promoting the conversion and excretion of cholesterol to bile acids, and regulating intestinal microbiota.
- Immune regulation and hematopoietic function promotion:
Polygonum multiflorum polysaccharides can regulate the body's immune function, enhance macrophage phagocytic ability, and lymphocyte transformation rate. At the same time, animal experiments have shown that it can promote the proliferation of bone marrow hematopoietic stem cells and has a certain protective and restorative effect on bone marrow suppression caused by chemotherapy or radiotherapy, providing modern evidence for "filling essence and supplementing marrow".
What Are the Applications of Polygoni Multiflori Preparata Extract?
Our Polygoni Multiflori Preparata Extract Powder is a versatile product that can be used in various ways. Here are some of its main applications:
- Health supplements
- Hair and skin care
- Traditional Chinese medicine
Common Product Dosage Forms
This extract powder has good solubility and compressibility, and is suitable for the preparation of various modern Chinese medicine formulations:
- Chinese herbal formula granules: Mix the extract powder with other single Chinese herbal formula granules according to the prescription for patients to take orally, which is currently one of the most convenient forms of application.
- Capsules/tablets: can be directly filled into capsules or mixed with suitable excipients to achieve precise dosage and convenient portability and administration.
- Pill/Oral Liquid: It can be used as the main ingredient to make traditional water pills, honey pills, or clear oral liquid preparations.
Why Choose APPCHEM?
Our Polygoni Multiflori Preparata Extract Powder is a versatile and potent natural product that can be used in various ways to support overall health and wellness. Its active ingredients have been scientifically studied for their antioxidant, anti-inflammatory, neuroprotective, and immune-boosting properties. Our product is of high quality and meets international standards, making it a reliable choice for merchants looking to offer their customers natural health supplements or hair and skin care products.
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Security statement:
Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.
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Reference
[1]Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota. Lingyu Ruan et al. [2025-05-22]
[2]Polygoni Multiflori Caulis: Quantitative Analysis and Quality Control Based on HPLC/UV/MS Fingerprinting. Zhang. [2013-06-24]
[3]X. Lei, Jing Chen et al. "Liver Damage Associated with Polygonum multiflorum Thunb.: A Systematic Review of Case Reports and Case Series." Evidence-based Complementary and Alternative Medicine: eCAM (2015). [2015-01-12]
[4]Kyoung-Ah Jung, H. Min et al. "Drug-Induced Liver Injury: Twenty Five Cases of Acute Hepatitis Following Ingestion of Polygonum multiflorum Thunb." Gut and Liver (2011). [2011-11-21]
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