Dihydromyricetin 98% Powder Dhm

Hovenia dulcis Extract Powder is a brown yellow to light-yellow powder made from dried Hovenia dulcis fruits or fruit stalks through standardised extraction, separation, concentration, and spray drying, with characteristic plant odour. This plant is rich in various bioactive components such as flavonoids, triterpenoid saponins, polysaccharides, and alkaloids. Among them, the fruit and stem parts have become key development targets in the field of functional foods and dietary supplements due to their high concentration of active ingredients and good safety.

Picture of Hovenia dulcis plant:

The core active ingredients of the product include dihydromyricetin (DHM), hovenoside series compounds, polysaccharide complexes, and tannic acid derivatives. The content of DHM is usually used as a key indicator for quality control, and the standard specification requirement is not less than 10%.

XI'AN APP-CHEM BIO (TECH) CO., LTD., as one of the first domestic enterprises to achieve industrial production of Fructus Aurantii extract, has its raw material base located in the geographical indication production area of the northern foot of Qinling Mountains, ensuring the traceability and batch stability of raw materials.

The most significant efficacy of Semen Hoveniae Extract is reflected in its preventive and reparative effects on alcoholic liver injury.

• Repair liver injury

Dihydromyricetin, as its core active ingredient, can enhance the antioxidant defence ability of liver cells by activating the Nrf2 ARE signalling pathway. Specifically, dihydromyricetin binds to specific cysteine residues in Keap1 protein, promoting Nrf2 nuclear translocation and upregulating the expression of heme oxygenase-1 (HO-1) and NAD (P) H: quinone oxidoreductase 1 (NQO1).

• Antioxidant Properties

The extract of Semen Hoveniae exhibits multi-target antioxidant properties. In vitro experimental data showed that its DPPH radical scavenging IC ₅₀ value was 28.4 μ g/mL, its iron ion chelating ability EC ₅₀ was 45.2 μ g/mL, and its total antioxidant capacity (TEAC value) reached 0.82 mmol Trolox/g.

• Blood glucose regulation

Hovenia dulcis Thunb extract showed significant improvement in the type 2 diabetes model. Dihydromyricetin, as a partial agonist of insulin-like growth factor receptor (IGF-1R), can activate the PI3K/Akt pathway, promote the translocation of glucose transporter 4 (GLUT4) to the cell membrane, and enhance glucose uptake in skeletal muscle and adipose tissue.

 

The efficacy of Semen Hoveniae Extract Powder

 

Repair liver injury

Antioxidant Properties

Blood glucose regulation

The powder of Semen Hoveniae Extract exhibits multidimensional application flexibility in the field of dietary supplements, and can be divided into the following categories based on the final product formulation:
1. Solid dosage

In hard capsule products, the powder of Fructus Aurantii extract is usually filled at a dosage of 300-400mg/capsule, either alone or in combination with extracts of Korean thistle and milk thistle, with the target functions of "liver health" and "sobering up and protecting the liver".
2. Powder and granules are suitable for sports nutrition and meal replacement scenarios.

Mixing the powder of Semen Hoveniae Extract with erythritol, citric acid, and natural fruit powder can produce a ready-to-dissolve functional solid beverage.
3. Functional beverages

Dissolve Semen Hoveniae Extract in purified water, add vitamin B group, taurine, electrolyte, and undergo UHT instantaneous sterilisation (135 ℃, 5 seconds) and sterile cold filling process to produce 200-500mL PET bottled sobering drinks.
4. Soft capsules and gel candies

Mix the extract of Semen Hoveniae with MCT oil and coenzyme Q10 to make soft capsules, each containing 100mg of extract, targeting the dual functions of liver repair and energy metabolism.

Security statement：

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.

Tags: Semen Hoveniae Extract, Hovenia dulcis Extract, dihydromyricetin manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk

Reference

[1]Hovenia dulcis Thunberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union. Gianluca Sferrazza et al. [2021]

[2]Physicochemical and Sensory Characteristics of Extract from Leaf, Fruit Stalk and Stem of Hovenia dulcis Thunb. Geum-Soon Park et al. [2005]

[3]Polyphenolic-Protein-Polysaccharide Complexes from Hovenia dulcis: Insights into Extraction Methods on Their Physicochemical Properties and In Vitro Bioactivities. Wu. [2020-04-08]

[4]Studies on the Chemical Characteristics of Hovenia (Hovenia dulcis) Honey Produced in Korea. Weon Ki Paik et al. [2015-02-04]

[5]Clinical Evaluation of Hovenia dulcis Extract Combinations for Effective Hangover Relief in Humans. Lee. [2024-12-12]

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