1. What is Epimedium Extract?
Epimedium sagittatum is a perennial herbaceous plant belonging to the Berberidaceae family and the Epimedium genus. It mainly grows in damp and shady areas such as mountain slopes and understory grasslands. As an important component of traditional Chinese medicine, Epimedium has a long history of medicinal use and is known for its effects of "tonifying kidney yang, strengthening muscles and bones, and dispelling wind and dampness".
Epimedium sagittatum Extract is a concentrated active ingredient obtained from the dried aboveground parts (including stems and leaves) of Epimedium sagittatum using modern extraction techniques.
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2. Certificate Of Analysis (COA)
The quality of Epimedium sagittatum extract is influenced by various factors, including the origin of the raw materials, harvesting time, and extraction process. Research has shown that there are significant differences in the chemical composition of Epimedium sagittatum from different regions. For example, the total flavonoid content of Epimedium sagittatum produced in the Fanjing Mountain area is relatively high, making it one of its high-quality germplasm resources. The harvesting time is also extremely critical. Traditional experience believes that the active ingredient content of medicinal herbs harvested during the summer and autumn, when the stems and leaves are lush, is the highest.[2]
|
Product Name |
Epimedium Extract (Epimedium P.E) |
|
ITEM |
SPECIFICATION |
|
Physical Description |
|
|
Appearance |
Brown powder |
|
Mesh Size |
95％ pass 80 mesh |
|
Taste |
Characteristic |
| Odor | Characteristic |
|
Chemical Tests |
|
|
Assay |
≥10.0% Icariin |
| 1-30:1 | |
|
Loss on drying |
≤5.0% |
|
Ash |
≤5.0% |
|
Heavy Metals |
≤10 ppm |
|
Pb |
≤2.0 mg/kg |
|
As |
≤1.0 mg/kg |
|
Hg |
≤0.3 mg/kg |
|
Microbiology Control |
|
|
Aerobic bacterial count |
≤1,000 CFU/g |
|
Total Yeast & Mold |
≤100 CFU/g |
|
Escherichia coli |
Negative |
|
Salmonella |
Negative |
3. Chromatogram of Icariin
4. What is the Process Flow Diagram?
The production process of the proportion extract of Epimedium sagittatum usually includes the following main steps:
4.1 Raw material pretreatment: Epimedium medicinal materials are selected, cleaned, dried, and crushed, usually requiring passing through an 80 mesh sieve to increase the extraction contact area.
4.2 Extraction: Use appropriate solvents (usually ethanol, water solutions of different concentrations, sometimes also water or ethanol-water mixed solutions) to extract under optimized conditions. Extraction may be carried out multiple times to ensure sufficient extraction of active ingredients.
4.3 Concentrate: Remove most of the solvent through methods such as vacuum concentration to obtain a concentrated extract.
4.4 Purification: As needed, further purification and enrichment of target components may be achieved through techniques such as macroporous adsorption resin and membrane separation, while removing impurities.
4.5 Protein removal: For polysaccharide components, it may be necessary to use enzymatic, Sevag, or macroporous resin methods to remove proteins.
4.6 Drying: The dried extract powder is obtained by spray drying, vacuum drying, or freeze drying.
4.7 Packaging and Storage: The product is stored in a dark, sealed container in a cool and dry warehouse.
5. Is Epimedium Extract Effective? How Does It Work?
The value of the proportion extract of Epimedium sagittatum as a dietary supplement is mainly based on its various pharmacological activities.
- Protective effect on bone health: Dehydrated icariin (AHI) is a natural isopentenyl flavonoid compound in Epimedium, which has strong anti-osteoporosis activity. Its mechanism of action involves promoting osteoblast differentiation, inhibiting osteoclast formation, and enhancing bone-forming activity.[3]
- Immune regulatory function: Epimedium polysaccharides are important immunologically active ingredients in Epimedium extracts. In the 2023 study, icariin polysaccharides were found to have immune-promoting activity, possibly by regulating the gut microbiota immune axis.[3]
- Anti-fatigue and endurance enhancement: Epimedium extract has traditionally been used to improve physical and mental fatigue. Due to these properties, it is used by some athletes and active individuals as a natural ergogenic aid.
6. What are the Applications of Epimedium sagittatum extract?
Epimedium sagittatum extract is commonly available in powder or liquid form when used as a dietary supplement. Powder extracts are easy to package, transport, and store, and can be easily processed into various dosage forms such as capsules, tablets, and powders. The extract is commonly used in oral liquids or beverages. According to market research in 2023, powder form dominates the global market for medicinal Epimedium extracts, accounting for over 70% of the market share.[1]
According to 2024 market data, global sales of herbal extracts and health products reached ¥16.2 billion, with projections indicating growth to ¥20.9 billion by 2030-reflecting a compound annual growth rate (CAGR) of 4.3%. In the Chinese market, major manufacturers such as Tonkin Health and Infinitus hold a significant market share.
Epimedium sagittatum extract can be formulated into various product forms, including capsules, tinctures, and tablets, to accommodate diverse consumer preferences and usage habits.
The extract of Epimedium sagittatum is often compounded with other components that have synergistic effects to enhance efficacy or expand functionality. Common compound ingredients include:
- Calcium and vitamin D synergistically support bone health with epimedium extract.
- Plant extracts such as astragalus, ginseng, and angelica offer broader health benefits through multi-herb synergy.
- Modern nutritional factors, such as collagen, glucosamine, chondroitin sulfate, etc., collectively support joint and bone health.
7. Why Choose APPCHEM?
APPCHEM (Nasdaq: BON), established in 2006, is a Nasdaq-listed manufacturer of botanical extracts focusing on the research, development, and production of plant-derived active ingredients for functional foods and personal care products.
Professional team
Our R&D engine is fueled by over 50% PhDs and advanced degree holders. Equipped with molecular distillation and nanofiltration systems, this team is responsible for 30+ national patents.
7x24 hours delivery
Located in 5 cities, providing 200+ languages,7x24 hours delivery capacity, is the best partner for enterprise globalization
13,500 m2
construction area
2
powder drinks production lines
2
special diets production lines
3
disinfection production lines
8. Certificates
Security statement：
Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.
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Reference
[1]Report on the Development Prospects and Risk Assessment of the Global and Chinese Medicinal Epimedium Extract Industry from 2023 to 2031
[2]Wang Lan, Chen Shixue, et al. Study on Optimizing the Extraction Process of total flavonoids in Epimedium sagittatum Maxim from Fanjing Mountain, Hubei Agricultural Sciences. (8):1968-1971
[3]Liting Ke, et al. Research progress on the extraction technology and activity study of Epimedium polysaccharides. Carbohydrate Polymers. 2023.01.18
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