Wholesale Price Natural Paeoniflorin Powder White Peony Root Extract

White Peony Root Powder is a highly sought-after natural product with numerous medicinal properties. For centuries, traditional Chinese medicine has recognized the white peony root extract as one of its most valuable herbal supplements. The extract powder is made from the root of the Paeonia lactiflora, a flowering plant native to China, which contains numerous compounds beneficial to the human body.

In recent years, the use of natural herbal extracts in modern medicine has increased significantly. This trend is attributed to the desire for a more personalized approach to healthcare as the search for more natural, side-effect profile medicines grows in popularity. White Peony Root Powder has become increasingly popular as it offers a wide range of health benefits, including anti-inflammatory and antioxidant properties, pain management capabilities, and a boost in the immune system, making it a valuable addition to any supplement line.

Modern plant chemistry research has isolated and identified over a hundred compounds from Paeonia lactiflora, mainly including monoterpenes and their glycosides, polyphenols, triterpenoids, sterols, etc. Among them, monoterpenes and their glycosides are the most important and representative active ingredients, with Total Glucosides of Peony (TGP) and Paeoniflorin as the core.[1,2]

• Total glucosides of Paeonia lactiflora (TGP): TGP is a general term for various glycosides in Paeonia lactiflora, including paeoniflorin, oxidized paeoniflorin, benzoyl paeoniflorin, etc. It is the main component of a natural medicinal preparation approved in China for the treatment of autoimmune diseases such as rheumatoid arthritis. A large number of pharmacological studies have confirmed that TGP is the key substance basis for white peony to exert anti-inflammatory and immune regulatory effects.[1] For example, the research published by Yu Xinran and others on traditional Chinese patent medicines and simple preparations in 2023 shows that TGP can effectively regulate the immune function of autoimmune thyroiditis rats.[2]

• Paeoniflorin: As the main monomer component in TGP, the content of Paeoniflorin is often used as a key indicator to evaluate the quality of Paeonia lactiflora and its extracts. Its pharmacological activity is extremely broad, covering multiple aspects such as neuroprotection, cardiovascular protection, anti-inflammatory, anti-tumor, etc. For example, according to the study published by Lu Yao et al. in the Chinese Journal of Veterinary Medicine in 2024, paeoniflorin showed significant protective effects on MPP+/MPPT induced Parkinson's disease model mice.[1] In addition, Li Lin et al. found in their study "Pharmacology and Clinical Practice of Traditional Chinese Medicine" in 2024 that paeoniflorin can improve endometrial receptivity in polycystic ovary syndrome rats by affecting the Wnt/β - catenin pathway.[1]

• Peony Polysaccharide: In addition to glycosides, Peony Polysaccharide is also one of its important active components. Research has shown that polysaccharides from Paeonia lactiflora have biological activities such as immune regulation, anti-tumor, and antioxidant properties.[1] Zeng Wanting et al. explored the protective effects of different ratios of Paeonia lactiflora polysaccharides and total glucosides of Paeonia lactiflora on subacute alcoholic liver injury in mice in the 2023 Chinese Prescription Drug, demonstrating its potential in liver protection.[2]

White Peony Root Powder contains antioxidants that help fight free radicals, the harmful substances that can cause inflammation and damage to cells. The anti-inflammatory properties of the extract powder make it an effective remedy for conditions such as arthritis, asthma, and allergies. It is also effective in reducing inflammation in the digestive system, which can help prevent and treat conditions such as irritable bowel syndrome, Crohn's disease, and ulcerative colitis.

The widespread application of Paeonia lactiflora root powder is rooted in its precise pharmacological activity. The research in the past three years has further deepened our understanding of its mechanism of action, mainly based on animal models and in vitro cell experiments.

4.1 Core efficacy: anti-inflammatory and analgesic effects

Anti-inflammation and analgesia are the most well-known effects of Paeonia lactiflora, and modern research provides solid molecular biology evidence for them. Total Paeoniflorin (TGP) and Paeoniflorin exhibit strong anti-inflammatory activity. Its mechanism is multi-target, including:

Inhibition of inflammatory factors: TGP can significantly inhibit the production and release of pro-inflammatory cytokines such as TNF-α, interleukin-1 β (IL-1 β), and interleukin-6 (IL-6).[1]

4.2 Immune System Regulation

Paeonia lactiflora is a famous immunomodulatory agent in traditional Chinese medicine, which has a bidirectional regulatory effect. It can inhibit excessive immune reactions and enhance the body's immunity.

TGP is widely used in the treatment of autoimmune diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus. TGP can correct the imbalanced ratio of helper T cells 17 (Th17) to regulatory T cells (Treg). A study published by Zhou Lijuan et al. in the Chinese Journal of Immunology in 2023 showed that TGP can improve the Treg/Th17 immune balance in mice with allergic purpura.[2]

4.3 Protective effects on the nervous system

In recent years, the protective potential of Paeonia lactiflora in neurological diseases has received much attention. Li Xuejing et al. confirmed in the 2021 Journal of Integrated Traditional Chinese and Western Medicine Cardiovascular and Cerebrovascular Diseases that total glucosides of Paeonia lactiflora have a protective effect on neuronal regeneration in the ischemic area of rats with cerebral ischemia-reperfusion injury.[2]

Anti-inflammatory effects

 

 

Immune System Regulation

 

 

Protective effects

Side-Effect Free

Unlike pharmaceutical drugs, which can have numerous side effects, White Peony Root Powder is safe to use and has no known side effects. It contains natural properties that are beneficial to the body without harsh effects on the liver or kidneys. This makes it an excellent natural alternative for individuals who are sensitive to traditional medications or anyone looking for a safe and effective supplement.

Easy to Use

Our White Peony Root Powder is easy to use and can be taken orally in capsule form or added to beverages, foods, or topical applications. It is also water-soluble, making it a versatile ingredient in many formulations.

White Peony Root Powder is a highly beneficial natural supplement with numerous medicinal properties. It offers several health benefits, including anti-inflammatory and antioxidant properties, pain management capabilities, immune system boosting, and a potent antimicrobial effect. It is safe to use, side-effect-free, easy to use, and sustainably made. Merchants looking to add natural supplements to their product lines should consider adding White Peony Root Powder to their store inventory. Our product's exceptional quality and ethical manufacturing practices make it the perfect addition to any sustainable and natural-oriented company.

The application history of Paeonia lactiflora can be traced back to the "Shennong Bencao Jing" during the Eastern Han Dynasty, which was classified as a top-grade product and recorded as "mainly used for treating abdominal pain caused by evil qi, removing blood stasis, breaking through hard deposits, cold and heat, hernia, relieving pain, promoting urination, and nourishing qi". Afterward, throughout history, white peony has occupied an important position in traditional Chinese medicine and is often combined with licorice to form the classic formula "Shaoyao Licorice Decoction", which is renowned for its "slow and urgent pain relief" effects.

Its plant source is the dried roots of peony. According to the regulations of the Pharmacopeia of the People's Republic of China (2020 edition), it is harvested in summer and autumn, washed, and the head, tail, and fine roots are removed. After boiling in boiling water and removing the outer skin, it is boiled again and dried in the sun. Its nature is bitter, sour, slightly cold, and it belongs to the liver and spleen meridians. It has the core effects of nourishing blood and regulating meridians, tonifying yin and stopping sweating, softening the liver and relieving pain, and calming liver yang.[1] The authentic production areas of Paeonia lactiflora are mainly concentrated in Anhui, Zhejiang, Sichuan, and other places in China. The climate and soil conditions of different production areas will have an impact on the quality and active ingredient content of Paeonia lactiflora.

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Reference
[1] Research progress on the chemical composition, pharmacological effects, and clinical applications of Paeonia lactiflora. Chen Qi, et al. [2021-04]
[2] Research progress on the pharmacological effects of Paeonia lactiflora and its chemical components. Shen Zixin, et al. [2024]
[3]Using Big Data to Analyze the Processing Technology, Chemical Composition, and Pharmacological Effects of Paeoniae Radix Alba. Caiqin Xiang et al. [2024]
[4] The effect of NE on peripheral synaptic transmission and epigenetic receptor dynamics of spinal motor neurons. Zhang Chuang, et al. [2023-04]

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