What is Phloretin Powder?
Natural Phloretin Powder is a highly effective ingredient in the skincare industry that has gained popularity in recent years. This versatile powder is derived from apples and is known for its outstanding antioxidant properties that can effectively protect the skin from damage caused by free radicals. Hence, this product is highly sought after and is becoming increasingly popular among many merchants who understand the benefits of using high-quality skincare ingredients in their products.
Our Natural Phloretin Powder has the ability to mitigate the effects of visible aging on the skin. This active ingredient promotes collagen synthesis, which ensures that the skin remains firm and supple. As the skin ages, collagen production naturally declines, which leads to fine lines, wrinkles, and sagging skin. Phloretin counters this by maintaining the production of collagen, which results in smoother, younger-looking skin.
Certificate Of Analysis (COA)
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Product Name |
Phloretin |
Botanical Source |
Malus pumila Mill. |
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CAS No. |
60-82-2 |
Plant Part |
Branch |
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ITEM |
SPECIFICATION |
RESULT |
TEST METHOD |
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Physical Description |
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Appearance |
Off-White Powder |
Conforms |
Visual |
|
Odor |
Characteristic |
Conforms |
Organoleptic |
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Taste |
Characteristic |
Conforms |
Olfactory |
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Particle size |
95% passes through an 80 mesh sieve |
Conforms |
CP2020 |
|
Chemical Tests |
|||
|
Assay |
≥90.0% |
92.33% |
HPLC |
|
Loss on drying |
≤1.0% |
0.38% |
CP2020 |
|
Ash |
≤1.0 % |
0.10% |
CP2020 |
|
Heavy Metals |
≤10 ppm |
Conforms |
CP2020 |
|
Lead (Pb) |
≤2ppm |
Conforms |
CP2020(AAS) |
|
Arsenic (As) |
≤1ppm |
Conforms |
CP2020(AAS) |
|
Cadmium (Cd) |
≤2 ppm |
Conforms |
CP2020(AAS) |
|
Mercury (Hg) |
≤1ppm |
Conforms |
CP2020(AAS) |
|
Microbiology Control |
|||
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Aerobic bacterial count |
≤1,000 cfu/g |
Conforms |
CP2020 |
|
Total Yeast & Mold |
≤100 cfu/g |
Conforms |
CP2020 |
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Escherichia coli. |
Negative |
Conforms |
CP2020 |
|
Salmonella |
Negative |
Conforms |
CP2020 |
|
Conclusion |
Conforms to specification |
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Storage: |
Store in tightly sealed and preferably full containers in a cool, dry, and ventilated area. |
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Shelf Life |
24 months when properly stored. |
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|
Status: |
Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified. |
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Is Phloretin Powder Effective? How Does It Work?
- Antioxidant:
Phloretin exerts potent antioxidant effects through multiple mechanisms. At the chemical level, the phenolic hydroxyl groups in its molecular structure can directly capture free radicals and neutralize DPPH, ABTS, and hydroxyl radicals through the hydrogen atom transfer (HAT) mechanism.
- Anti-inflammatory:
Phloretin exerts strong anti-inflammatory effects by inhibiting the NF-κB signaling pathway, as well as inhibiting COX-2 enzyme activity and reducing prostaglandin E ₂ (PGE ₂) synthesis.
- Anti-aging:
The anti-aging effect of Phloretin is achieved through three mechanisms: firstly, its antioxidant activity can clear free radicals and prevent oxidative cross-linking of collagen and elastin; Secondly, by inhibiting the expression of MMP-1 and MMP-3, UV-induced extracellular matrix degradation can be reduced; Finally, activating the TGF - β/Smad pathway promotes the synthesis of type I and III collagen by fibroblasts.
Why Choose APPCHEM?
Appchem's Natural Phloretin Powder is an ideal ingredient for merchants looking to provide their customers with effective, high-quality skincare products.
It is essential to note that our Natural Phloretin Powder is free from harmful chemicals, such as parabens, sulfates, and artificial fragrances. This aspect of our product makes it an attractive ingredient for merchants looking to provide consumers with natural, high-quality skincare products. This powder is also vegan and cruelty-free, which further appeals to the growing number of consumers who prioritize ethical and sustainable products.
We are Phloretin experts
XI'AN APP-CHEM BIO (TECH) CO., LTD. (APPCHEM) is headquartered in Xi'an High-tech Zone, Shaanxi Province, with an independent R&D center and testing laboratories. Its Dali and Tongchuan production sites cover a total area of nearly 20,000 square meters, and it operates through the marketing networks in and out of China.
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17K+ m²Building area
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20 +Years
What is the Market Prospect of Phloretin?
With the increasing market share of plant-based functional cosmetics, phloretin has successfully attracted the attention of researchers in the beauty industry with its multi-functional beauty effects. Studies have found that phloretin has various pharmacological effects, such as anti-oxidation, anti-tumor, anti-inflammation, immunosuppression, and promotion of bone formation. In addition, it also has the effects of whitening and acne removal.
Phloretin is not only used in whitening and anti-aging products but also in acne-removing or soothing cosmetics. Of course, according to literature reports, phloretin also has the functions of moisturizing, anti-hair loss, antibacterial, and sun protection. You can also see many products containing phloretin on the market, such as SkinCeuticals Whitening Repairing Day Serum, SkinCeuticals Phloretin CF, and Avon.
Certificates
Security statement：
Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.
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FAQ
Q: What is the difference between Phloretin and phlorizin? How to choose cosmetics?
A: Phloretin is the glycoside form of phlorizin, with a smaller molecular weight and stronger skin permeability. Phloretin has direct biological activity, while phlorizin needs to be converted into root bark extract under the action of skin microorganisms to exert its effect. For formulas that pursue quick results, it is recommended to choose phloretin; For sustained-release or sensitive muscle formulations, phlorizin may be milder.
Q: What is the optimal amount of Phloretin added to the formula? How to ensure its stability?
A: According to efficacy testing data, it is recommended to add 0.1-0.5% for whitening products, 0.2-0.3% for anti-aging products, and 0.05-0.1% for soothing products. Root bark extract is unstable to light, heat, and strong alkali. It is recommended to control the pH of the formula between 5.0-6.5, add chelating agents (such as EDTA-2Na) to prevent metal ion catalytic oxidation, and use opaque packaging or add light stabilizers (such as BHT) to improve photostability.
Q: What is the shelf life of Phloretin products? What are the special requirements for storage conditions?
A: Under sealed, dark, cool, and dry conditions, the shelf life of root bark extract powder is 24 months.
Q: Is Phloretin suitable for all skin types? Are there any taboos for use?
A: Phloretin is suitable for most skin types, including oily, combination, and normal skin. For extremely sensitive skin, it is recommended to perform a local patch test first. Due to the potential impact of Phloretin on cellular metabolism, pregnant and lactating women are advised to use it under the guidance of a doctor.
Reference
[1]M. Jung, S. Triebel et al. "Influence of apple polyphenols on inflammatory gene expression." Molecular nutrition & food research (2009). [2009-10-01]
[2]Synthèse chimio-enzymatique, purification et caractérisation de molécules analogues aux métabolites secondaires du bois de co-produits de l'arboriculture pour des applications cosmétiques. Laurène MINSAT. [2022-11-10]
[3]Wei-Tien Chang, Wen-Chung Huang et al. "Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages." Food chemistry (2012). [2012-09-15]
[4]Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions. Zarros.
