Andrographis Paniculata Extract Andrographolide

Andrographis Paniculata Extract Andrographolide is a natural plant extract derived from the leaves and stems of Indian Andrographis (Andrographis paniculata). Its primary active component, Andrographolide, has become a significant botanical active ingredient in dietary supplements and health products due to its pronounced anti-inflammatory, antioxidant, antiviral, and immunomodulatory effects.

APPCHEM's Andrographis Paniculata Extract Andrographolide concentrates on isolating and concentrating the core active ingredient Andrographolide. Through scientific solvent extraction, multi-stage separation, and purification techniques, it is meticulously extracted from the leaves and stems of Indian Andrographis, ensuring high purity and stability. APPCHEM employs standardised extraction processes with stringent control over Andrographolide content in each batch, meeting the high-quality requirements of diverse dietary supplement and health product formulations.

Andrographis Paniculata Extract Andrographolide is typically supplied in powder or granule form, offering excellent formulation compatibility and processing adaptability. It is suitable for use in various dietary supplements and functional foods, including tablets, capsules, and granules, serving as a key ingredient in formulations targeting anti-inflammatory, immune-enhancing, and antioxidant properties. Combined with other herbal extracts or nutritional components, Andrographis Paniculata Extract Andrographolide is widely utilised in formulations designed to support the immune system, alleviate inflammatory responses, and enhance the body's antiviral defences.

XI'AN APP-CHEM BIO (TECH) CO., LTD. (APPCHEM) provides Andrographis Paniculata Extract Andrographolide utilising a mature, reproducible industrial plant extraction process, comprising the following principal steps:

• Washing
• Filtering
• Removing impurities
• Drying: to prevent high-temperature damage to thermosensitive active ingredients, especially volatile oils.
• Crushing: (such as 80 mesh) to increase the contact area with the solvent and improve extraction efficiency.
• Extraction
• Solid-liquid separation
• Purification
• Concentrate
• Drying
• Smashing
• Packaging
• Finished product

Andrographis Paniculata Extract Andrographolide derives its application value in dietary supplements primarily from its potent immunomodulatory and anti-inflammatory properties. Its mechanism of action is complex and sophisticated, involving multi-target and multi-pathway regulation, which underpins its broad spectrum of health benefits.

• Potent Immunomodulatory Function

Andrographis Paniculata Extract Andrographolide demonstrates bidirectional regulatory potential for the human immune system, simultaneously enhancing defensive capabilities while preventing excessive immune responses. It promotes lymphocyte proliferation, enhances macrophage phagocytic capacity, and may activate natural killer (NK) cell activity-all forming the body's primary defences against foreign pathogens. Furthermore, it modulates adaptive immune responses, such as influencing T-cell and B-cell functions, enabling more precise targeting of specific threats.

• Exceptional Anti-inflammatory Activity

One of Andrographolide's core anti-inflammatory mechanisms lies in its potent inhibition of the nuclear factor-κB (NF-κB) signalling pathway. By inhibiting pathways such as NF-κB, Andrographis Paniculata Extract Andrographolide significantly reduces the production of multiple pro-inflammatory cytokines and mediators, including tumour necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), and prostaglandins (via suppression of cyclooxygenase-2/COX-2 expression). These mediators are the direct executors of inflammatory responses such as redness, swelling, heat, and pain. By lowering their levels, Andrographolide helps alleviate inflammatory symptoms and maintain bodily equilibrium.

• Antimicrobial Activity and Respiratory Health Support

Building upon its traditional properties of clearing heat and detoxifying, modern research confirms that Andrographis Paniculata Extract Andrographolide possesses broad-spectrum antimicrobial activity. This renders it an ideal component for supporting respiratory health. As a dietary supplement, it is not intended to treat disease but rather maintains a healthy environment within the respiratory and digestive tracts by bolstering the body's natural defence systems.

To maximise the market potential of Andrographis Paniculata Extract Andrographolide, we advise clients to focus on high-demand health sectors based on its exceptional efficacy, whilst adopting diverse product formats to cater to varying consumer preferences.

Target Application Areas: Consistent with our market positioning, Andrographis Paniculata Extract Andrographolide serves as an ideal core or adjunct ingredient within the following product lines:

• Immune Support Line:

Product formats: Daily immune maintenance capsules/tablets; seasonal rapid-response powders/oral solutions.

• Joint Health & Inflammation Management Line:

Product Forms: Joint Relief Capsules, Post-Exercise Recovery Powder.

• Respiratory Health Line:

Product Forms: Throat & Lung Cleansing Capsules, Respiratory Comfort Syrup/Drops.

• Liver Health Line:

Product Forms: Liver Purification & Protection Capsules.

The product is mainly in the form of standardised plant extract powder and supports customisation of content, making it easy for OEM/ODM customers to design formulas.
 

Security statement：

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.

Hot Tags: Andrographis Paniculata Extract Andrographolide, manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk.

Long-term cooperative logistics companies include international logistics companies such as DHL, FedEx, UPS, etc.

The regular bulk packaging of the product is a 25kg plastic bag and a cardboard drum. The sample is packaged in an inner aluminium foil bag and an outer plastic bag, supporting customised packaging solutions.

XI'AN APP-CHEM BIO (TECH) CO., LTD. (APPCHEM) regularly participates in international raw material exhibitions such as CPHI, SSW, and In Cosmetics Asia, and establishes long-term cooperative relationships with global customers.

Q1. How is the purity of this product verified?
A1: We employ authoritative analytical methods such as High Performance Liquid Chromatography (HPLC) and Ultraviolet Spectroscopy (UV) to ensure a content of 98%.

Q2. What is the minimum order quantity for Andrographis Paniculata Extract Andrographolide?
A2: Our minimum order quantity (MOQ) varies by product and specific requirements, and is typically negotiable. Don't hesitate to get in touch with us for detailed information.

Q3. What is the delivery timeframe for the product?
A3: Delivery times vary depending on the order volume and product type. Generally, we arrange production and dispatch promptly upon order confirmation.

Q4. Does APPCHEM offer customisation services?
A4: Yes, we provide customisation services including packaging, labelling, and adjusting product specifications to meet specific client requirements.

Q5. How does APPCHEM ensure product quality and stability?
A5: We maintain a rigorous quality control system. All products undergo third-party testing, with detailed COA (Certificate of Analysis) and stability data provided.

Reference
[1]Xiaohong Li, Weicheng Yuan et al. "Andrographolide, a natural anti-inflammatory agent: An Update." Frontiers in Pharmacology (2022).
[2]R. Yadav, Susanta Sadhukhan et al. "Exploring the mechanism of andrographolide in the treatment of gastric cancer through network pharmacology and molecular docking." Scientific Reports (2022).
[3]Sunghwan Kim, P. Thiessen et al. "PubChem Substance and Compound databases." Nucleic Acids Research (2015).
[4]M. Low, C. Khoo et al. "An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure andrographolide." BMC Complementary and Alternative Medicine (2015).
[5]A. Varma, H. Padh et al. "Andrographolide: A New Plant-Derived Antineoplastic Entity on Horizon." Evidence-based Complementary and Alternative Medicine: eCAM (2011).