Pure 90% Asiaticoside Powder

Pure 90% Asiaticoside Powder

Specification: (Purity) 95%
CAS number: 16830-15-2
Other name: Madecassol
Appearance: Brown Powder
Application: Medical, health care, food

Annual Supply Capacity: 20MT
Packing: 25KG/Fiber Drum, Foil bag
Storage: Keep dry and cool
Shelf Life: 24 Months
Botanical Source: Centella Asiatica

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Description
Technical Parameters

Historically, Centella Asiatica belongs to the Umbelliferae family. The botanist Linnaeus (Carolus) classified Centella Asiatica into the genus Hydrocotyle in 1764 and named it Hydrocotyle asiatica L. In 1879, the German botanist separated it from Hydrocotyle based on the arrangement of the petals and the number of edges of the fruit, and established the genus Centella asiatica.

1. What is Asiaticoside Powder?

  • Distribution area:

Centella asiatica is primarily distributed in tropical and subtropical regions of the northern and southern hemispheres, with its main production areas including South Africa, India, Sri Lanka, Malaysia, Indonesia, Australia, and Japan. China also produces Centella asiatica.

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The chemical composition of Centella Asiatica is complex, mainly including triterpenoids, flavonoids, volatile oils, polyphenenes, and so on. Among them, triterpenoids are the main medicinal ingredients, including asiaticoside, asiaticoside A, wave thermomoside, wave heat rice glycoside, ginsenoside, isoginsenoside, asiatic acid, hydroxyl Centella asiatica acid, Madara asiatic acid, etc.

 

Molecular formula: C48H78O19
Molecular weight: 959.12
EINECS number: 240-851-7

 

2. Certificate Of Analysis (COA)

Product Name

Centella Asiatica Extract

Batch Size

500 kg

CAS No.

N/A

Batch No.

AP20241013

Botanical Source

Centella asiatica(L)

MFG. Date

Oct. 13, 2024

Plant Part

Whole Herb

Retest Date

Oct. 12, 2026

Country of Origin

China

Issue Date

Oct. 20, 2024

ITEM

SPECIFICATION

RESULT

TEST METHOD

Physical Description

Appearance

Light Brown or white Powder

Conforms

Visual

Odor

Characteristic

Conforms

Organoleptic

Taste

Characteristic

Conforms

Olfactory

Particle size

95% passes through an 80 mesh sieve

Conforms

CP2020

Chemical Tests

Assay

≥98.0%

98.19%

HPLC

Loss on drying

≤5.0%

2.45%

CP2020 (105 oC, 3 h)

Ash

≤3.0%

2.17%

CP2020 (600 oC, 4 h)

Heavy Metals

≤20 ppm

Conforms

CP2020

Lead (Pb)

≤1 ppm

Conforms

CP2020(AAS)

Arsenic (As)

≤1 ppm

Conforms

CP2020(AAS)

Cadmium (Cd)

≤0.1 ppm

Conforms

CP2020(AAS)

Mercury (Hg)

≤0.1 ppm

Conforms

CP2020(AAS)

Microbiology Control

Aerobic bacterial count

≤1,000 cfu/g

Conforms

CP2020

Total Yeast & Mold

≤100 cfu/g

Conforms

CP2020

Escherichia coli.

Negative

Conforms

CP2020

Salmonella

Negative

Conforms

CP2020

Conclusion

Conforms to specification

Storage

Store in tightly sealed, preferably full containers, in a cool, dry, and well-ventilated area.

Shelf Life

24 months when properly stored.

Status

Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified.

 

3. What is the Process Flow Diagram?

The acquisition of high-quality Asiaticoside Powder relies on a precise and optimized production process. This process aims to maximize the extraction of target components while removing impurities, ensuring high purity and activity of the final product. The typical process is as follows:
 

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4. Is Asiaticoside Powder Effective? How Does It Work?

The health benefits of Asiaticoside have been supported by numerous modern pharmacological studies that reveal its complex mechanisms of action at the molecular and cellular levels.

Core efficacy and scientific mechanism of action

 

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Neuroprotection and Cognitive Support

Asiaticosis can upregulate the expression of endogenous antioxidant enzymes in cells by activating the Nrf2/HO-1 signaling pathway, thereby clearing harmful free radicals and protecting neurons from oxidative damage.

A study published in the journal Antioxidants in 2021 confirmed that Asiaticoside inhibits cell apoptosis in retinal degeneration through this pathway.[1]

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Wound Repair and Skin Health

 

Asiaticosis can significantly stimulate the proliferation of fibroblasts and promote the synthesis of type I collagen. A study published in International Immunology in 2020 found that Asiaticoside can accelerate the healing of diabetic skin ulcers by activating the Wnt/β-catenin signaling pathway. [1] This pathway plays a central role in cell proliferation, migration, and tissue regeneration.

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Anti-Inflammatory and Bone Health

 

Recent studies have further revealed its potential applications in bone health. An experimental study has shown that Asiaticoside exhibits potential anti-osteoporosis effects by inhibiting the RANKL-induced NFATc1 and NF-κB signaling pathways, thereby suppressing osteoclast generation and function.[1

 

5. What are the Applications of Asiaticoside Powder?

With its diverse biological activities, Asiaticoside Powder has a wide range of applications and values in multiple major health fields.

5.1 Dietary supplements:

  • Cognition and Brain Health: As an ingredient of "Nootropics", it is used to develop capsules, tablets, or powder products that support memory, focus, and delay cognitive aging.
  • Beauty and skin health: In "oral beauty" or "inside out" beauty products, it is used to promote skin repair, moisturization, and anti-aging, often in the form of capsules, gummies, or beauty drinks.
  • Joint and connective tissue support: Utilizing its properties of promoting collagen synthesis and anti-inflammation, it can be used in composite formula products to support joint health and maintain tendon and ligament function.
  • Anti-aging and overall health: As a broad-spectrum antioxidant and anti-inflammatory ingredient, it can be added to daily multidimensional supplements or anti-aging formulas.

5.2 Functional foods and beverages:

It can be added to functional beverages, health energy bars, meal replacement powders, and other products to provide additional health benefits to food, catering to consumers who pursue convenient, efficient, and healthy lifestyles.

5.3 Cosmetics and Personal Care (External Use):

The high-purity Asiaticoside Powder is also the core ingredient of high-end repair and anti-aging cosmetics. It is widely used in essence, face cream, facial mask, and other products to relieve sensitivity, repair barriers, and fade scars and wrinkles.[2]

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6. Certificates

certificates

Security statement:

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.

Tags: Asiaticoside Powder, Asiaticoside Powder manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk.

 

Qualification

Reference
[1]PHYTOCHEMISTRY AND MEDICINAL PROPERTIES OF CENTELLA ASIATICA. Md Munan Shaik et al.
[2]A Review on Centella Asiatica Plant and Its Chemical Constituents and Related Products in Cosmetology. Rudroju Anusha et al. [2024-11-09]
[3]Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial. A.S. et al. [2023-02-01]

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