What is Fructus Cnidii Extract?
Fructus Cnidii Extract is a natural active ingredient derived from the dried and ripe fruit of the Apiaceae plant Cnidium monnieri (L.) Cuss. As a herbaceous plant with thousands of years of use in traditional Chinese medicine, snake bed has been used for warming the kidneys and strengthening yang, drying dampness and dispelling wind, killing insects, and relieving itching.
In recent years, with the deepening of modern plant chemistry and pharmacology research, Fructus Cnidii Extract has gradually become a star ingredient in the global dietary supplement, functional food, and personal care product markets due to its clear active ingredients and extensive biological activities.
Main active ingredient
The core value of Fructus Cnidii Extract lies in its rich range of bioactive compounds, among which coumarins are particularly crucial and abundant.
- Osthole:
Numerous modern pharmacological studies have confirmed that Osthole has a wide range of biological activities, including, but not limited to, anti-inflammatory, anti-allergic, anti-tumour, anti-osteoporotic, neuroprotective, cardiovascular function-improving, and sexual function-enhancing. The commercially available Fructus Cnidii Extract usually uses the content of snake bed extract as its core quality standard, with various specifications ranging from conventional 10%, 35% to high-purity 98%.
- Other coumarin components: In addition to osthole, osthole also contains various other structurally related or synergistically acting coumarins, such as Bergapten, Xanthotoxin, Isoprinelin, and Imperatorin.
Market positioning and application prospects
In the field of dietary supplements, the positioning of Fructus Cnidii Extract is very clear and diversified. It is not only a traditional male health support ingredient used to enhance energy and vitality; Its powerful anti-inflammatory and antioxidant properties have shown great potential for application in niche markets such as sports nutrition, joint health, skin health, and immune support.
For example, its anti-inflammatory effect can be used to relieve muscle soreness after exercise, while its anti-allergic and anti-itching properties are suitable for oral beauty products that improve skin health.
Certificate Of Analysis (COA)
|
Product Name |
Fructus Cnidii Extract | Botanical Source | Cnidium monnierl L. Cuss |
|
CAS No. |
484-12-8 |
Plant Part |
Seed |
|
ITEM |
SPECIFICATION |
RESULT |
TEST METHOD |
|
Physical Description |
|||
|
Appearance |
White powder |
Conforms |
Visual |
|
Mesh Size |
95％ pass 80 mesh |
Conforms |
CP2020 |
|
Taste |
Characteristic |
Conforms |
Olfactory |
|
Chemical Tests |
|||
|
Assay(Baicalin) |
≥98.0% |
98.63% |
HPLC |
|
Loss on drying |
≤5.0% |
3.12% |
CP2020 (65 ℃, 3h) |
|
Ash |
≤5.0% |
0.59% |
CP2020 (600℃, 4h) |
|
Heavy Metals |
≤10 ppm |
<10 ppm |
CP2020 |
|
Pb |
≤2.0 mg/kg |
Conforms |
GB 5009.75 |
|
As |
≤1.0 mg/kg |
Conforms |
GB 5009.76 |
|
Hg |
≤0.3 mg/kg |
Conforms |
GB 5009.17 |
|
Microbiology Control |
|||
|
Aerobic bacterial count |
≤1,000 CFU/g |
<10 CFU/g |
CP2020 |
|
Total Yeast & Mould |
≤100 CFU/g |
<10 CFU/g |
CP2020 |
|
Escherichia coli |
Negative |
Conforms |
CP2020 |
|
Salmonella |
Negative |
Conforms |
CP2020 |
|
Conclusion |
Conforms to specification |
||
|
Storage: |
Store in a cool, dry, well-ventilated area; keep in tightly sealed containers, preferably full. | ||
|
Shelf Life: |
24 months when properly stored. |
||
|
Status: |
Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified. |
||
What is the Process Flow Diagram?
In order to efficiently and stably convert the valuable active ingredients in Fructus Cnidii Seed into standardised commercial raw materials, the industry has developed and optimised a series of extraction processes. A typical industrial production process aims to maximise the yield and purity of target components (mainly coumarins such as osthol), while effectively removing impurities and ensuring the safety of the final product.
Overview of Process Flow
- Raw material pretreatment
- Extraction
- Filtration
- Concentration
- Purification
- Drying
- Crushing
- Inspection
- Packaging
Is Fructus Cnidii Extract Effective? How Does It Work?
The multiple health benefits of Fructus Cnidii Extract are rooted in its core active ingredients, especially osthol, which exhibits powerful physiological regulatory functions through complex biological mechanisms involving multiple targets and pathways.
Product efficacy
Application Fields and Product Forms
With its diverse biological activities and clear mechanism of action, Fructus Cnidii Extract has a wide range of applications in dietary supplements and related health industries. The product forms are also flexible and versatile, which can meet the needs of different consumer groups.
Main application areas
- Male health supplements: usually combined with ingredients such as arginine, maca extract, and icariin extract to synergistically enhance efficacy.
- Sports nutrition and recovery: Its anti-inflammatory properties make it an ideal ingredient for post-exercise recovery products. The product can be in the form of protein powder additives, sports drinks, or specialised recovery capsules.
- Bone and Joint Health: Often combined with calcium, vitamin D3, vitamin K2, glucosamine and other ingredients to make tablets or capsules.
- Oral beauty and skin health: The anti-inflammatory, anti-allergenic, and antioxidant properties of Fructus Cnidii Extract make it suitable for use in oral beauty products that improve skin condition.
- Personal care products: In the field of external use, Fructus Cnidii Extract is widely added to herbal ointments, detergents, private care liquids, and functional shampoos, utilising its antibacterial, anti-inflammatory, and anti-itch effects.
Common product forms
1. Capsules/tablets: This is the most common and convenient dosage form, easy to quantify and carry. It can be made into single or compound products.
2. Powder: It can be used as a standalone packaged granule or added as a functional ingredient to protein powder, meal replacement powder, and solid beverages.
3. Oral liquid/functional beverage: Fructus Cnidii Extract is made into a liquid form, which absorbs faster and has an adjustable taste, suitable for people who do not like to swallow capsules.
4. Gummies: As an emerging and more popular dosage form among young consumers, the functional gummies market is growing rapidly.
Why Choose APPCHEM?
- Excellent supply chain management and cost advantages: APPCHEM is headquartered in Xi'an, Shaanxi, located in the core area of China's abundant plant resources. APPCHEM has established long-term and stable cooperative relationships with raw material production areas to develop contract agriculture, ensuring the quality of raw materials and the stability of supply from the source.
- Advanced technology platform and quality assurance: APPCHEM has four major technology platforms for efficient manufacturing, safety, activity enhancement, and formulation technology of natural active ingredients, covering a series of advanced production technologies from membrane separation to efficient countercurrent extraction.
- Solid production foundation and capacity layout: APPCHEM has two production bases in Weinan and Tongchuan that have been put into operation, and is currently building a production base in Yumen, Gansu. This "multi-point layout" strategy not only ensures sufficient production capacity to meet different order demands from kilograms to tons, but also enhances the supply chain's ability to resist risks.
XI'AN APP-CHEM BIO (TECH) CO., LTD.
Bon Natural Life(Nasdaq: BON)
The Company is headquartered in Xi'an High-tech Zone, Shaanxi Province, with an independent R&D centre and testing laboratories. Its Dali and Tongchuan production sites cover a total area of nearly 20,000 square meters, and it operates through the marketing networks in and out of China.
DALI FACTORY
- Covering 30 acres and a building area of 11000 m²
- Having a plant extract workshop, a precision drying and packaging workshop, and a spice refining workshop
TONGCHUAN FACTORY
- Covering 20 acres, with a construction area of 6900 m²
- Having 3 clean workshops, 2 formula product production lines, and 1 special food production line under construction.
2006
SINCE
17,900 m²
Building area
90M
Order received
30+
Patents
Certificates
Security statement：
Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.
Tags: Fructus Cnidii Extract, Osthol manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk.
FAQ
Q: Is Fructus cnidii extract and Osthole the same thing?
A: Not entirely. Fructus cnidii extract is a mixture containing multiple active ingredients, among which osthol is the most important and representative single chemical component. You can think of Fructus cnidii extract as a 'team', and Cnidii is the 'star player' in this team.
Q: How long will Fructus cnidii extract take to see results?
A: The manifestation time of the effect varies depending on individual differences, dosage, product formula, and expected health goals.
Q: Can Fructus cnidii extract be taken together with other dietary supplements?
A: Yes, fructus cnidii extract has good compatibility and is often combined with various dietary supplement ingredients to achieve synergistic effects. For example, in men's health products, it is compounded with maca and arginine; Compound with glucosamine and chondroitin sulfate in joint health products.
Q: How to choose high-quality Fructus cnidii extract products?
A: When choosing high-quality products, please pay attention to the following points: 1. Clear active ingredient content: The label should clearly indicate the content of Osthole, such as 10%, 35%, or 98%. 2. Reliable supplier: Choose well-known raw material suppliers with strong production capabilities and strict quality control systems, such as BON NATURAL LIFE. 3. Third-party testing report: A reliable supplier can provide a third-party testing report (COA) for the product, proving that its active ingredient content meets the standard and that safety indicators such as heavy metals and pesticide residues are qualified.
Reference
[1]Effects of Cnidium monnieri (L.) Cuss. fruit (Fructus Cnidii) extract on male erectile function in experimental animals [Efectos del extracto de fruto de Cnidium monnieri (L.) Cuss. (Fructus Cnidii) sobre la función eréctil masculina en animales de experimentación. Duong T. Dau et al. [2025]
[2]Advances in Research on the Identification of Cnidii Fructus and Its Adulterants. Weiwei HE et al. [2023-09-15]
[3]Optimal extraction and fingerprint analysis of Cnidii fructus by accelerated solvent extraction and high-performance liquid chromatographic analysis with photodiode array and mass spectrometry detections. et al. [2024-01-01]
[4]H. Matsuda, Y. Ido et al. "Antipruritic effect of Cnidii Monnieri Fructus (fruits of Cnidium monnieri CUSSON).." Biological & pharmaceutical bulletin (2002). [2002-02-01]
[5]Establishment of a Process for Separation and Extraction of Coumarins from Cnidii Fructus by Cloud-Point Preconcentration Using Self-Microemulsion as Solvent. [2013-08-24]
