What is Panax Quinquefolius Extract?
In today's unprecedentedly high global awareness of health and wellness, the dietary supplement market is undergoing a profound transformation from basic vitamins and minerals to more functional, scientifically proven, and naturally sourced raw materials. In this trend, the concept of "Adaptogen" has become the focus of market pursuit due to its unique ability to help the body resist various physical, chemical, and biological stressors and maintain physical and mental balance. Panax quinquefolius L., as a star member of the Panax genus in the Araliaceae family, is an outstanding representative of the adaptogen family.

Plant Origin and Historical Background
American ginseng is a perennial herbaceous plant native to the broad-leaved forests of eastern North America. Its application history can be traced back several centuries, initially widely used by Native Americans in North America to enhance physical fitness and treat various diseases. Unlike Asian ginseng, which is mainly produced in Asia and belongs to the category of "warming and tonifying" in traditional Chinese medicine theory, Panax Quinquefolius Extract is famous for its "cooling" or "nourishing without causing excessive internal heat" properties.
Core active ingredient
The biological activity of American Ginseng or Panax Quinquefolius Extract is mainly attributed to a unique set of steroidal saponins it contains - ginsenosides. Scientific research has identified dozens of ginsenoside monomers from American ginseng using advanced analytical techniques such as high-performance liquid chromatography-mass spectrometry (LC/MS/MS), including ginsenosides Rb1, Re, Rg1, Rc, Rb2, Rd, Rh1, and the unique pseudo-ginsenoside F11 (p-F11).
Structural formula:

Certificate Of Analysis (COA)
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General Information |
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Name |
Panax Quinquefolius Extract |
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Part used |
Root |
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Item |
Specification |
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Appearance |
Light Yellow Powder |
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Flavor & Odor |
Characteristic |
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Particle Size |
95% pass 80 mesh |
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Physical |
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Loss on Drying |
≤5.0% |
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General Status |
Non-irradiated |
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Chemical |
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Pb |
≤3mg/kg |
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As |
≤1mg/kg |
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Hg |
≤0.1mg/kg |
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Cd |
≤1mg/kg |
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Microbial |
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Total microbacterial count |
≤1000cfu/g |
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Yeast & Mold |
≤100cfu/g |
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E.Coli |
Negative |
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Staphylococcus aureus |
Negative |
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Salmonella |
Negative |
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Enterobacteriaceaes |
Negative |
What is the Process Flow Diagram?
A superior natural extract raw material, its value lies not only in the excellent quality of the raw material itself, but also in whether it can preserve and enrich its core active ingredients to the maximum extent through advanced and scientific production processes, while removing ineffective or even harmful impurities.
- Fresh fruits are washed.
- Filter
- Remove impurities
- Drying: to prevent high-temperature damage to thermosensitive active ingredients, especially volatile oils.
- Crushing: (such as 80 mesh) to increase the contact area with the solvent and improve extraction efficiency.
- Core extraction
- Solid-liquid separation
- Purification
- Concentrate
- Drying
- Smash
- Packaging
- Finished product
Is Panax Quinquefolius Extract Effective?
The value of American ginseng extract as a dietary supplement ingredient is rooted in its multi-target and multi-pathway biological effects. The following will focus on several of its most widely recognised benefits in the field of modern health and the scientific mechanisms behind them, to distinguish it from its vague description in traditional medicine.
The efficacy of Panax Quinquefolius Extract




4.1 Regulating the HPA Axis, Intelligent Stress Resistance
The core function of "adaptogen" is to help the body maintain homeostasis. The high-intensity stress of modern life can excessively activate the hypothalamic pituitary adrenal (HPA) axis, leading to long-term high levels of stress hormones such as cortisol, which can cause a series of sub-healthy problems such as anxiety, fatigue, insomnia, and weakened immunity.
4.2 Enhancing Cognitive Function
Brain health is one of the fastest-growing segments in the field of functional foods and supplements. Panax Quinquefolius Extract has shown great potential in improving memory, concentration, and cognitive flexibility, making it an ideal ingredient for the development of natural Nootropics products.
4.3 Optimising Energy Metabolism
Unlike central stimulants such as caffeine that "refresh" the body by overdrawing energy, Panax Quinquefolius Extract fundamentally optimises energy metabolism to combat fatigue and provide a smooth and lasting vitality.
4.4 Auxiliary Blood Glucose Health Management
Maintaining healthy blood sugar levels is key to preventing metabolic syndrome and maintaining long-term health. The extract of American ginseng has shown encouraging application prospects in this field.
What Are the Applications of Panax Quinquefolius Extract?
With its clear health benefits and high safety, APPCHEM's Panax Quinquefolius Extract can be widely used in multiple segmented fields of dietary supplements and functional foods, providing strong support for brand innovation.
- Core application areas
1. Emotional Health and Stress Management:
As a core application, it can be developed into anti-stress products in the form of capsules, tablets, oral liquids, etc.
2. Brain Health and Cognitive Support (Puzzle Products):
It can be used to develop memory support formulas for middle-aged and elderly people, or efficient learning and work performance improvement products for young people.
3. Energy supplementation and exercise nutrition:
It can be used as a key ingredient in decaffeinated energy drinks, pre-exercise supplements, or restorative drinks.
4. Blood sugar health and metabolic support:
It can be developed as a capsule or powder product to assist in stabilising blood sugar, especially suitable for people who are concerned about blood sugar health and weight management.
5. Immune Health and Daily Health Care:
As the basic ingredient of daily immune regulation products, it is suitable for all age groups to enhance long-term physical fitness.
Company Strengthen
In natural plant Extract
The Company is headquartered in Xi'an High-tech Zone, Shaanxi Province, with an independent R&D centre and testing laboratories. Its Dali and Tongchuan production sites cover a total area of nearly 20,000 square meters, and it operates through the marketing networks in and out of China.
XI'AN APP-CHEM BIO (TECH) CO., LTD.
Bon Natural Life (Nasdaq: BON)

+ m²
+
Certificates

Security statement:
Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.
Hot Tags: Panax Quinquefolius Extract, American Ginseng Extract manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk

FAQ
Q: What is the difference between the American ginseng extract from APPCHEM and the Asian ginseng extract on the market?
A: There are two main differences. Firstly, the source and characteristics are different: our American ginseng extract is derived from North American Panax quinquefolius, which has a "cool" nature and is suitable for long-term, mild nourishment, and is not easily prone to overheating; Asian ginseng extract is derived from Panax ginseng, which has a "warm" nature and strong nourishing effects. Secondly, the core ingredient profiles are different: our product is rich in PPD type saponins such as Rb1, which have more advantages in calming and relieving stress, while Asian ginseng has a higher content of PPT type saponins such as Rg1, which have a more pronounced excitatory effect.
Q: What is the recommended daily dosage?
A: Based on reference information from international regulations such as FSSAI in India and scientific literature, we recommend setting the recommended daily intake of terminal products between 90-400 milligrams of American ginseng extract.
Q: Can this extract be used for liquid products such as beverages?
A: Sure. In addition to standard powders suitable for capsules and tablets, we can also provide high water solubility specification products that have been specially processed to ensure that they can dissolve quickly in cold water, clear and transparent, and have a pure flavour. They are very suitable for developing functional beverages, oral liquids, solid beverages, and other liquid or instant soluble products.
Reference
[1]A. Attele, J. A. Wu et al. "Ginseng pharmacology: multiple constituents and multiple actions.." Biochemical pharmacology (1999).[1999-12-01]
[2]PHYTOCHEMICAL VARIATION AND IMMUNOPHARMACOLOGY OF PANAX QUINQUEFOLIUS L. (AMERICAN GINSENG). Valerie Ann et al.[2001-12]
[3]X. Wang, T. Sakuma et al. "Determination of ginsenosides in plant extracts from Panax ginseng and Panax quinquefolius L. by LC/MS/MS.." Analytical chemistry (1999).[1999-03-16]
[4]Bioactive Polysaccharides of American Ginseng Panax quinquefolius L. in Modulation of Immune Function: Phytochemical and Pharmacological Characterisation. Edmund M. K. Lui et al.[2012]
[5]Proceedings of The Future of Ginseng and Forest Botanicals Symposium. Alison Ormsby et al.[2017-07-12]

