1. Products Description
Natural Sclareolide Powder, also known as dionein, is an organic compound and a naturally occurring sesquiterpene lactone. It is found in various plants and is widely used in the production of various products, including perfumes and as a food ingredient. Sclareolide has a similar structure and composition to other terpenes and is composed of a tricyclic ring system. It has a strong odor, with a musky and slightly sweet scent, and is often used as a base note in various perfumes.
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Melting Point:121℃-124 ℃ |
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CAS number:564-20-5 |
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Molecular formula: C16H26O2 |
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Molecular weight:250.38 |
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EINECS/ELINCS Registration Number:209-269-0 |
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Structural formula: |
2. Certificate of Analysis(COA)
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Product Name |
Sclareolide |
Botanical Source |
Salvia Sclare L. |
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CAS No. |
564-20-5 |
Plant Part |
Flower and Cormus |
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ITEM |
SPECIFICATION |
RESULT |
TEST METHOD |
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Physical Description |
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Appearance |
White Powder |
Conforms |
Visual |
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Odor |
Characteristic |
Conforms |
Organoleptic |
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Taste |
Characteristic |
Conforms |
Olfactory |
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Particle size |
100% pass through 80 mesh sieve |
Conforms |
CP2020 |
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Physical Tests |
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Melting Point |
121℃-124 ℃ |
121℃-123 ℃ |
CP2020 |
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Specific Rotation |
+38 o ~ +42 o |
+40 o |
CP2020 |
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Solubility |
Soluble (1g in 100 ml of absolute Ethanol) |
Conforms |
CP2020 |
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Chemical Tests |
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Assay |
≥98.0% |
98.26% |
GC |
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Loss on drying |
≤0.3% |
0.16% |
CP2020(105 ℃, 3 h) |
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Ash |
≤0.3% |
0.06% |
CP2020(600 ℃, 4 h) |
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Heavy Metals |
≤10 ppm |
Conforms |
CP2020 |
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Microbiology Control |
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Aerobic bacterial count |
≤1,000 CFU/g |
Conforms |
CP2020 |
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Total Yeast & Mold |
≤100 CFU/g |
Conforms |
CP2020 |
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Escherichia coli |
Negative |
Conforms |
CP2020 |
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Salmonella |
Negative |
Conforms |
CP2020 |
3. Process Flow Chart of Sclareolide

4. Feature of Sclareoilide
Natural Sclareolide Powder is known to possess antimicrobial, anti-inflammatory, anti-hyperplastic, and antifungal properties. It is used in the medical treatment of several conditions, such as arthritis, psoriasis, and a variety of skin diseases. In addition, Sclareolide has antioxidant and antiproliferative activities and is used in many skincare products. Sclareolide is also used in the food industry as a flavoring agent and a preservative, as it has antimicrobial properties and is also known to increase the shelf life of food products. It is also used as a preservative in cosmetic products and some plant-based products.
One of the main advantages of Sclareolide is its natural origin. It is obtained from plants and is non-toxic, making it a safe ingredient in many products. In addition, it is a cost-effective and readily available ingredient and does not need to be synthesized for use. Sclareolide is widely used in various products, including perfumes, food, cosmetics, and plant-based products. It is used to increase the shelf life of food products and as a fragrance base in perfumes. It is also used to treat various skin conditions, such as acne and psoriasis, due to its antimicrobial and anti-inflammatory properties. In addition, it is known to have antioxidant and antifungal properties and is often used in skincare products.
5. Application of Sclareolide
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▲Natural Sclareolide Powder is an important chemical compound found in the essential oil of clary sage. It has a distinctly earthy, sweet, floral, herbal, and woody odor. It is widely used as a perfumery ingredient to impart a fresh and pleasant aroma to cosmetics, perfumes, and fragrances.
▲Sclareolide has also been used extensively in the pharmaceutical and food industries. In pharmaceuticals, its use is mainly as a topical anesthetic and antiseptic. It has also been used to treat a variety of disorders, including respiratory infections and skin diseases. In the food industry, it has proven to be effective as an insect repellent.
▲Sclareolide is an important component of many fragrances, perfumes, and cosmetics. It is used to lend an earthy and sweet aroma to perfumes, fragrances, and soaps. Additionally, it is also a key ingredient in musk, Fougere, oriental, and marine fragrances.
▲Due to its pleasant odor and low cost, Sclareolide has also been used as a fragrance in a wide variety of personal care products such as shampoo, conditioner, body wash, and lotion. It has also been used to impart a long-lasting fragrance to laundry detergents and fabric softeners.
▲Sclareolide has also been studied for its therapeutic benefits. It has been shown to exert an anti-inflammatory effect when applied topically and can protect the skin against UV damage. In vitro studies suggest that it can also act as an antifungal and antiviral agent. Furthermore, there is evidence that Sclareolide has sedative, anti-anxiety, and antidepressant properties.
▲Overall, Sclareolide is a versatile compound used in the personal care, pharmaceutical, and food industries. Its sweet and earthy aroma makes it a popular ingredient in fragrances and perfumes. Additionally, it is known for its anti-inflammatory, antifungal, antiviral, and sedative effects and is an effective insect repellent. Finally, its low cost makes it an attractive option for personal care products and laundry detergents. |
6. Certificates

Security statement:
Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.
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Reference
[1]Natural Raw Materials in the Flavor and Fragrance Industry. Kurt Bauer et al. [2001]
[2]Low sclareol by-product of clary sage concrete: chemical analysis of a waste product of the perfume industry. Rémi Laville et al. [2012]
[3]Natural Products in the Chemical Industry. Bernd Schaefer. [2014]
[4]Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture. Anne Caniard et al. [2012]
[5]RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-5. A.M. Api et al. [2022-08-19]




