1. What is Natural Sclareol powder?

Natural Sclareol powder is a white crystalline powder extracted from the natural Labiate Salvia sclarea L. It has a faint, delicate amber fragrance with strong diffusivity and a lasting smell, which can give a vivid, harmonious, and lasting fragrance to the essence.
It is mainly used in synthesizing substitutes for natural ambergris, such as Sclareolide and Ambroxide(Ambroxan), and is less used in preparing essence. In the field of medicine, it is used for antibacterial and anti-inflammatory, choleretic, and anticancer properties. In the field of pesticides, it is used to prevent and control crop rust and powdery mildew, kill insects, mediate plant growth activity, and plant defense function activity.
Clary Sage is also known as Southern European Salvia, Rosette Sage. Biennial or perennial herb of the Lamiaceae Salvia genus, about 1-2 meters high, with lignified lower stems, erect, branched, and the whole plant is covered with short hairs. Single leaves opposite, oval or oblong. Inflorescences, bisexual flowers, pink or light purple or white, bracts broadly ovate, corolla snow-blue. Nutlets are ovoid, taupe, and smooth. The flowering period is from June to July. The seed maturity period is July. Light-loving, cold-tolerant, drought-tolerant, barren-resistant, and afraid of waterlogging. Seedlings are not shade-tolerant. Native to southern Europe. Introduced in the 1950s in my country, it is currently distributed in Shaanxi, Hebei, Henan, Zhejiang, and other provinces. Especially the clam basil that grows in the shallow mountainous area of northern Shaanxi.
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Melting point: m.p. 95~105ºC |
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CAS number: 515-03-7 |
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Molecular formula: C20H36O2 |
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Molecular weight: 308.51 |
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EINECS/ELINCS Registration Number: 208-194-0 |
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Structural formula: |
2. Certificate Of Analysis (COA)
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Product Name |
Sclareol |
Botanical Source |
Salvia sclare L. |
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CAS No. |
515-03-7 |
Plant Part |
Flower and Cormus |
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ITEM |
SPECIFICATION |
RESULT |
TEST METHOD |
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Physical Description |
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Appearance |
White Powder |
Conforms |
Visual |
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Odor |
Characteristic |
Conforms |
Organoleptic |
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Taste |
Characteristic |
Conforms |
Olfactory |
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Particle size |
95% passes through an 80 mesh sieve |
Conforms |
CP2020 |
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Physical Tests |
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Melting Point |
95℃-105℃ |
96℃~98℃ |
CP2020 |
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Specific Rotation |
-9°~-13° |
-11° |
CP2020 |
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Chemical Tests |
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Assay |
≥98.0% |
98.42% |
GC |
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Loss on drying |
≤0.3% |
0.10% |
CP2020 (90 ℃, 3 h) |
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Ash |
≤0.3% |
0.06% |
CP2020 (600℃, 4 h) |
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Heavy Metals |
≤10 ppm |
<10 ppm |
CP2020 |
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Microbiology Control |
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Aerobic bacterial count |
≤1,000 CFU/g |
Conforms |
CP2020 |
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Total Yeast & Mold |
≤100 CFU/g |
Conforms |
CP2020 |
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Escherichia coli |
Negative |
Conforms |
CP2020 |
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Salmonella |
Negative |
Conforms |
CP2020 |
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Conclusion |
Conforms to specification |
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Storage: |
Store in tightly sealed and preferably full containers in a cool, dry, and ventilated area. |
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Shelf Life |
24 months when properly stored. |
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Status: |
Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified. |
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3. What is the Process Flow Diagram?

The production method of Sclareol involves steam distillation or extraction from the essential oil of clary sage plants. The first step in producing Sclareol is to extract the essential oil from the plant material using either steam distillation or solvent extraction. Steam distillation requires boiling water, which creates steam that passes through the plant material, extracting its volatile molecules, such as Sclareol, along with other compounds present in it. Solvent extraction uses a chemical solvent like hexane to separate out the desired component, such as Sclareol, from other substances present within the plant material. After obtaining an essential oil containing high levels of Sclareol, fractional distillation can be utilized to isolate this compound further so that purer samples can be obtained.
4. Chromatogram

5. Is Natural Sclareol Powder Effective? How Does It Work?
Sclareol is a natural compound that has been used in traditional medicine for centuries. It comes from the clary sage plant and is mainly found in the essential oil of this herb. Over the years, researchers and scientists have extensively studied clary sage and discovered many beneficial properties of this compound.
One of the most important functions of clary sage is its ability to act as an anti-inflammatory agent. This means that it can reduce inflammation-related swelling and redness, which helps alleviate pain and discomfort caused by diseases such as arthritis or tendinitis. In addition, studies have shown that Sclareol may help treat certain skin diseases, such as acne, as it has antibacterial effects on harmful bacteria present on the surface of the skin. The antioxidant properties of clary sage are another reason why it is widely used in traditional medicines around the world. Neutralizing free radicals within cells helps protect them from damage, which, if not controlled, may lead to chronic diseases or illnesses. In addition, studies have shown that clary sage may be able to improve cognitive abilities by increasing levels of acetylcholine (a neurotransmitter) in the brain, which could be invaluable for those suffering from memory loss or other similar issues related to brain aging.
However, more research is needed before any clear conclusions can be drawn! However, there is no doubt that when used responsibly under appropriate medical supervision, there are many reasons why you should consider adding perilla to your daily life!
6. What Are the Applications of Natural Sclareol Powder?
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▲Used in flavors, spices, cigarettes, cosmetics, health food, food additives, etc. ▲Used in the synthesis of sclareolide and Ambroxide (Ambroxan). ▲It is used in the synthesis of ambergris-amber fragrances. It is more suitable for use in perfume essences when using its fragrance-fixing properties for direct fragrance adjustments. |
7. Certificates

Security statement:
This product is a natural plant extract, non-toxic, harmless, and with no flammable or explosive danger. Any safety accidents and injuries caused by the standard use of our products shall be borne by our company. This product does not belong to the psychotropic, narcotic, stimulant, precursor chemicals, or chemical weapons products, and is not the raw material for the manufacture of psychotropic, narcotic, stimulant, precursor chemicals, or chemical weapons products. Non-toxic, non-corrosive, non-oxidizing, non-radioactive, no harm to the human body and environment, and no danger to air transportation. The above content and declaration are true. If the declaration content is not true, our company shall bear all the legal responsibility for any adverse consequences.
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