Pure Ferulic Acid Powder

Pure Ferulic Acid Powder

Specification: (Purity)98%
CAS number: 1135-24-6
Appearance: White or Off-White Powder
Application: Health care, Fragrance, Cosmetic Materials

Annual Supply Capacity: 80MT
Packing: 25KG/Fiber Drum, Foil bag
Storage: Keep dry and cool
Botanical Source: Oryza sativa L.
Plant Part: Seed

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Description
Technical Parameters

What is Ferulic Acid Powder?

Pure Ferulic Acid Powder is known for its skin protective properties. When used topically, ferulic acid is said to treat sunburn and reverse signs of aging, including fine lines and wrinkles. Ferulic acid is less commonly used as an oral supplement, but it is thought to improve athletic performance and slow the aging process. Also, ferulic acid is sometimes used to prevent or treat certain health conditions.

 

Ferulic acid comes in two types: cis and trans. The cis form is a yellow oil, and the trans form is a square crystal or a fibrous crystal. Ferulic acid is a ubiquitous aromatic acid in the plant kingdom and is a constituent of suberin. It rarely exists in the free state in plants and mainly forms a bound state with oligosaccharides, polyamines, lipids, and polysaccharides.   

Chemical name: 4-hydroxy-3-methoxy cinnamic acid

Ferulic_acid_3D_Structural formula

Molecular formula: C10H10O4

Molecular weight: 194.18

EINECS/ELINCS Registration Number:214-490-0

Structural formula:

 

 

Market Positioning

In the essence flavor industry chain, pure ferulic acid powder is positioned as a high-end functional raw material, mainly serving international large-scale essence companies and domestic leading enterprises. Its core values are reflected in three aspects:

  • As a natural antioxidant, it can effectively replace synthetic antioxidants such as BHT and BHA, meeting the trend demand for clean labels.
  • As a fragrance stabilizer, its phenolic hydroxyl structure can form weak hydrogen bond complexes with aldehydes and ketones, which can slow the rate of aroma volatilization and prolong the fragrance retention time of Eau de essence for 2-3 hours.
  • In tobacco essence and fermented essence, ferulic acid can be used as a precursor to participate in the Maillard reaction to generate unique baking flavor and nutty flavor.

 

 

Certificate Of Analysis (COA)

Product Name

Ferulic acid

Botanical Source

Oryza sativa L.

CAS No.

1135-24-6

Plant Part

Seed

ITEM

SPECIFICATION

RESULT

TEST METHOD

Physical Description

Appearance

White or Off-White Powder

Conforms

Visual

Odor

Characteristic

Conforms

Organoleptic

Taste

Characteristic

Conforms

Olfactory

Particle size

95% passes through an 80 mesh sieve

Conforms

CP2020

Chemical Tests

Assay

≥99%

99.05%

HPLC

Loss on drying

≤1.0%

0.30%

CP2020 (105 oC, 3 h)

Ash

≤0.5%

0.14%

CP2020 (600 oC, 4 h)

Heavy Metals

≤20 ppm

Conforms

CP2020

Lead (Pb)

≤2 ppm

Conforms

CP2020(AAS)

Arsenic (As)

≤2 ppm

Conforms

CP2020(AAS)

Cadmium (Cd)

≤1 ppm

Conforms

CP2020(AAS)

Mercury (Hg)

≤1 ppm

Conforms

CP2020(AAS)

Microbiology Control

Aerobic bacterial count

≤1,000 cfu/g

Conforms

CP2020

Total Yeast & Mold

≤100 cfu/g

Conforms

CP2020

Escherichia coli

Negative

Conforms

CP2020

Salmonella

Negative

Conforms

CP2020

Conclusion

Conforms to specification

Storage:

Store in tightly sealed and preferably full containers in a cool, dry, and ventilated area.

Shelf Life:

24 months when properly stored.

Status:

Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified.

 

Is Ferulic Acid Effective? How Does It Work?

▲Skin Protection

A topical ointment containing ferulic acid and vitamin E reduced the number of skin lesions by about 20% in mice exposed to intense ultraviolet B (UVB) radiation. When used alone, vitamin E actually increased the number of lesions by about 15%. Although this seemed to suggest that ferulic acid could reverse sun damage, the researchers never included mice tested with ferulic acid alone. Therefore, studies can only prove that ferulic acid can reduce the damage caused by vitamin E on severely sunburned skin.

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▲Reduce Hypertension

One study suggests that ferulic acid may help lower blood pressure. Hypertensive rats treated with ferulic acid for eight weeks had significantly lower systolic blood pressure, increased blood flow to the kidneys, and stiffness in the left ventricle of the heart (the part of the heart where blood is pumped into the body in the aorta). Despite the positive findings, it is unclear whether the same effect can be achieved in humans.

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▲Lower blood fat

Pure Ferulic Acid Powder can competitively inhibit the activity of valonate-5-pyrophosphate dehydrogenase in the liver, and inhibit the synthesis of cholesterol in the liver, so as to achieve the purpose of lowering blood lipids.

 

 

▲Antibacterial effect

The inhibitory effect of ferulic acid on bacteria is broader-spectrum. It has been found that ferulic acid can inhibit Shigella sonnei, Klebsiella pneumoniae, Enterobacter, Escherichia coli, Citrobacter, Pseudomonas aeruginosa, etc. Disease-causing bacteria and 11 microorganisms that cause food spoilage.

 

▲Pharmacological effect

Pure Ferulic Acid Powder has the functions of inhibiting platelet aggregation, expectorant, and inhibiting Mycobacterium tuberculosis. Clinically, ferulic acid is mainly used for adjuvant treatment of arteriosclerosis, coronary heart disease, cerebrovascular disease, glomerular disease, pulmonary hypertension, diabetic vascular disease, vasculitis, and other vascular diseases, as well as leukopenia and thrombocytopenia. It can be used for the treatment of migraine and vascular headaches. As a leukocyte-increasing drug, this drug also has the effect of enhancing hematopoietic function. Therefore, ferulic acid can also be used in the treatment of white blood cells and thrombocytopenia.

What Are the Applications of Ferulic Acid Powder?

Ferulic acid has many health functions, such as scavenging free radicals, antithrombosis, antibacterial and anti-inflammatory, inhibiting tumors, preventing hypertension and heart disease, enhancing sperm motility, etc.

Professional application of essence and fragrance

In a high-end perfume flavoring system, ferulic acid is used as a "fixative synergist".

  • Case 1: According to the patent (WO2023/078901) disclosed by Givaudan in 2023, the addition of 0.03-0.08% ferulic acid in Dongfang Diao perfume can prolong the scent retention time of synthetic musks such as sandalwood 208 and ambergris ketone by 40%, while enhancing the "warmth" and "powder" of the aroma. 
  • Case 2: Ferulic acid can be mainly used for baking, nuts, and sauce flavor essence. Adding 0.01% ferulic acid to bread essence can not only prevent fat from rancidity, but also generate 2,5-dimethyl-4-hydroxy-3 (2H) - furanone (furanone) in the Maillard reaction, which endows the product with natural caramel aroma and increases the sensory evaluation score by 15%.
  • Case 3: In the tobacco essence, when ferulic acid accounts for 0.05-0.1% of the total formula, it can inhibit the oxidation of nicotine and maintain the original flavor of tobacco. The data is quoted from the technical paper collection of Yunnan China Tobacco Industry Co., Ltd. in 2023.

Application of Cosmetics and Daily Chemicals

The performance of ferulic acid in cosmetics can prove its safety and versatility.

The study in Journal of Biochemistry and Photobiology B: Biology, Volume 235, 2022 (authored by Kim JH's team at Seoul National University in South Korea) confirmed that ferulic acid can form stable phenoxide free radicals under UVB radiation, which do not degrade on their own, while protecting phthalate sunscreen agents, reducing their photodegradation rate from 45% to 12%.

Ferulic Acid Powder 1

 

Certificates

certificates

Security statement:

Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.

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Qualification

 

Product Usage Guide

Storage conditions

taboos

shelf life

usage quantity

Compatible ingredients

APPCHEM

Storage conditions and shelf life

 

Pure ferulic acid powder should be stored under sealed, dark, and dry conditions. According to the accelerated stability test data of Tianmei Biology, the product is stored at 40 ℃± 2 ℃/75% RH ± 5% for 6 months. The appearance, content, and related substances of the product meet the quality standards, and the shelf life at room temperature (25 ℃) is 24 months

Compatible ingredients

 

Ferulic acid is well compatible with most natural essential oils (lavender oil, tea tree oil, peppermint oil), synthetic fragrances (sandalwood 803, muscone), and antioxidants (vitamin E, rosemary extract). It has good solubility in ethanol, propylene glycol, and DPG (dipropylene glycol) and can be prepared into a 10% mother liquor for use.

Compatibility taboos

 

Avoid direct contact with strong oxidants such as benzoyl peroxide and sodium hypochlorite.

Unstable in strongly alkaline systems with pH>8.5, prone to decarboxylation reaction to produce 4-vinylguaiacol, resulting in odor.

Complexation with certain metal ions (Fe ³ ⁺, Cu ² ⁺) may cause color changes. It is recommended to add EDTA-2Na (0.02%) as a chelating agent.

Recommended usage quantity

 

In perfume and light essence, the recommended dosage is 0.02-0.08%;

0.01-0.05% in shampoo and conditioner essence;

0.03-0.10% in fabric care essence;

0.005-0.02% in edible essence (baking, nuts).

The specific dosage shall be adjusted according to the total oil concentration of the essence, solvent system, and customer stability requirements.

 

Reference

[1]S. Chowdhury, Sumit Ghosh et al. "Ferulic Acid Protects Hyperglycemia-Induced Kidney Damage by Regulating Oxidative Insult, Inflammation and Autophagy." Frontiers in Pharmacology (2019). [2019-02-05]

[2]C. Mancuso, R. Santangelo. "Ferulic acid: pharmacological and toxicological aspects." Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association (2014). [2014-03-01]

[3]S. Réhman, T. Ali et al. "Ferulic Acid Rescues LPS-Induced Neurotoxicity via Modulation of the TLR4 Receptor in the Mouse Hippocampus." Molecular Neurobiology (2018). [2018-07-30]

[4]Jun-Hui Choi, Jong-Kook Park et al. "In vitro and in vivo antithrombotic and cytotoxicity effects of ferulic acid." Journal of Biochemical and Molecular Toxicology (2018). [2018-01-01]

[5]Vanisree Staniforth, Wen-Ching Huang et al. "Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin via posttranslational mechanisms." The Journal of Nutritional Biochemistry (2012). [2012-05-01]

[6]Surajit Das, Annie B. H. Wong. "Stabilization of ferulic acid in topical gel formulation via nanoencapsulation and pH optimization." Scientific Reports (2020). [2020-07-23]

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