What is Grape Seed Extract 95 OPC?
Grape Seed Extract 95% OPC is a high-potency proanthocyanidin plant extract derived from grape seeds through standardised extraction and purification processes, achieving an oligomeric proanthocyanidin (OPCs) content of up to 95%. As a premium-grade product within grape seed extracts, this ingredient is widely utilised in the cosmetics sector for anti-ageing, antioxidant, and skin barrier repair formulations, owing to its highly concentrated active components and stable quality parameters.
Compared to conventional grape seed extracts, the 95% OPC grade Grape Seed Extract demonstrates distinct advantages in ingredient purity, biological activity, and formulation efficiency. Proanthocyanidins are a class of oligomeric polyphenolic compounds possessing potent free radical scavenging capabilities. Their antioxidant activity is considered significantly superior to traditional antioxidants such as vitamins C and E. In skincare formulations, high-purity OPCs more effectively participate in the skin's antioxidant defence system, helping mitigate skin ageing caused by UV exposure, pollution, and oxidative stress.
Feature
Grape Seed Extract 95% OPC typically presents as a light brown to reddish-brown powder, readily soluble in water or alcohol-containing systems, making it suitable for diverse cosmetic formulations. Its polyphenolic structure confers excellent antioxidant stability to products, maintaining high activity levels under appropriate formulation systems and storage conditions. Furthermore, this ingredient boasts clear sourcing and consistent batches, meeting fundamental cosmetic raw material requirements for safety, traceability, and quality consistency.
Certificate Of Analysis (COA)
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General Information |
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Name |
Grape Seed Extract 95% OPC |
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Part used |
Seeds |
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Item |
Specification |
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Appearance |
Reddish-brown Powder |
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Odor |
Characteristic |
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Taste |
Characteristic |
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Particle Size |
95% pass 80 mesh |
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Physical |
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Loss on Drying |
≤5.0% |
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Sulphated Ash |
≤5.0% |
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Chemical |
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Pb |
≤3mg/kg |
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As |
≤1mg/kg |
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Hg |
≤0.1mg/kg |
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Cd |
≤1mg/kg |
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Microbial |
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Total microbacterial count |
≤1000cfu/g |
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Yeast & Mold |
≤100cfu/g |
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E.Coli |
Negative |
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Staphylococcus aureus |
Negative |
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Salmonella |
Negative |
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Enterobacteriaceaes |
Negative |
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Conclusion |
Conforms to specification |
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Storage: |
Store in a cool, dry, well-ventilated area; keep in tightly sealed containers, preferably full. |
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Shelf Life: |
24 months when properly stored. |
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Status: |
Non-irradiation; Non-GMO; No Carrier; Halal & Kosher certified. |
What is the Process Flow Diagram?
XI'AN APP-CHEM BIO (TECH) CO., LTD. (APPCHEM) provides Grape Seed Extract 95 OPC utilising a mature, reproducible industrial plant extraction process, comprising the following principal steps:
- Washing
- Filtering
- Removing impurities
- Drying: to prevent high-temperature damage to thermosensitive active ingredients, especially volatile oils.
- Crushing: (such as 80 mesh) to increase the contact area with the solvent and improve extraction efficiency.
- Extraction
- Solid-liquid separation
- Purification
- Concentrate
- Drying
- Smashing
- Packaging
- Finished product
Is Grape Seed Extract 95 OPC Effective?
Benefits of Grape Seed Extract 95 OPC



- Superior antioxidant capacity, neutralising free radicals
The molecules within Grape Seed Extract 95% OPC are rich in phenolic hydroxyl groups. These phenolic hydroxyl groups act as highly efficient hydrogen donors, reacting extremely rapidly with free radicals to reduce them into stable, harmless molecules. This interrupts the free radical chain reaction, blocking oxidative damage at its source. Multiple studies indicate that OPCs' antioxidant capacity significantly surpasses that of traditional vitamins C and E. This exceptional capability makes them an ideal choice for combating extreme environmental stressors.
- Protecting and Promoting Collagen and Elastin
OPCs effectively inhibit the activity of collagenase and elastase. Research on grape seed proanthocyanidins revealed an IC50 value of 38 μM for collagenase inhibition, demonstrating significant enzymatic suppression. By inhibiting these destructive enzymes, OPCs directly safeguard the structural integrity of existing collagen and elastin. In vitro studies further indicate that grape seed extract stimulates fibroblast proliferation while upregulating the gene expression and protein synthesis of type I collagen and elastin.
- Defence Against UV Damage
Grape Seed Extract 95% OPC is neither a chemical nor a physical sunscreen; it does not directly absorb or reflect ultraviolet radiation. Its photoprotective action operates at an "endogenous" level, mitigating the cascade of internal skin damage triggered by UV exposure. OPCs neutralise UV-induced free radicals through potent antioxidant and anti-inflammatory properties, reducing DNA damage and apoptosis. Simultaneously, they inhibit UV-triggered inflammatory pathways, mitigating erythema and sunburn reactions. Furthermore, they suppress the expression of UV-activated MMPs such as collagenase, preventing excessive collagen degradation following sun exposure.
What Are the Applications of Grape Seed Extract 95 OPC?
Grape Seed Extract 95% OPC, with its multifunctionality and high compatibility, can be widely incorporated into various cosmetic formulations, empowering brands to create star products with exceptional efficacy.
1. Premium Anti-Ageing Series:
- Product Types: Serum, Wrinkle Repair Cream, Luxury Eye Cream, Neck Care Cream.
- Formulation Examples: Can be blended with peptides, retinol and its derivatives, and boswellia to synergistically enhance efficacy, creating comprehensive anti-ageing solutions.
2. Daily Defence & Anti-Pollution Series:
- Product Types: Day Protection Emulsion, Urban Protective Cream, Antioxidant Serum, Sunscreen.
- Formulation Examples: Incorporating this into sunscreen formulations broadens photoprotection. Combining with Ectoin, ergothioneine and similar ingredients constructs a robust environmental stress defence system.
3. Brightening & Even-Tone Series:
- Product Types: Brightening Serum, Spot-Reducing Mask, Tone-Correcting Lotion.
- Formulation Example: Its tyrosinase-inhibiting mechanism complements classic brightening agents like Vitamin C, Niacinamide, and Kojic Acid, suppressing melanin production and transfer at multiple targets.
4. Soothing & Repairing Series:
- Product Types: Sensitive Skin Cream, After-Sun Repair Gel, Soothing Mask.
- Formulation Example: Leveraging its anti-inflammatory properties, it pairs effectively with Centella Asiatica extract, Bisabolol, and ceramides to deliver gentle yet potent care for sensitive and compromised skin.
5. Hair & Scalp Care:
Product Type: Scalp Anti-Ageing Serum, Anti-Hair Loss Shampoo, Conditioner.
Claims: Protects scalp cells from oxidative damage, strengthens hair roots, and maintains a healthy scalp microbiome.
The product is primarily available in the form of standardised plant extract powder, allowing for customisation of OPC content, making it easy for OEM/ODM customers to design their own formulas.
Factory Strength
The Company is headquartered in Xi'an High-tech Zone, Shaanxi Province, with an independent R&D centre and testing laboratories. Its Dali and Tongchuan production sites cover a total area of nearly 20,000 square meters, and it operates through the marketing networks in and out of China.
DALI FACTORY
Covering 30 acres and a building area of 11000 m²
Having a plant extract workshop, a precision drying and packaging workshop, and a spice refining workshop
TONGCHUAN FACTORY
Covering 20 acres, with a construction area of 6900 m²
Having 3 clean workshops, 2 formula product production lines, and 1 special food production line under construction

2006
Since
17,900 m²
Building area
90M
Order received
30+
Patents
Certificates

Security statement:
Our company guarantees that the goods sent are safe, non-flammable, and non-explosive, and consistent with the declaration. Under normal transportation conditions, all losses caused by the products sent by our company shall be borne by our company.
Hot Tags: Grape Seed Extract, 95% OPC, OPC, manufacturers, suppliers, factory, wholesale, best, price, buy, for sale, bulk.

Shipping and Packaging
Long-term cooperative logistics companies include international logistics companies such as DHL, FedEx, UPS, etc.

The regular bulk packaging of the product is 25kg plastic bag+cardboard drum, and the sample is 1-10kg inner packaging aluminium foil bag and outer packaging plastic bag, supporting customised packaging solutions.

Exhibition
XI'AN APP-CHEM BIO (TECH) CO., LTD. (APPCHEM) regularly participates in international raw material exhibitions such as CPHI, SSW, and In Cosmetics Asia, and establishes long-term cooperative relationships with global customers.

FAQ
Q1: Is Grape Seed Extract 95% OPC safe for sensitive skin?
A1: Yes, it is entirely safe. According to the final assessment report by the authoritative Cosmetic Ingredient Review (CIR), Grape Seed Extract 95% OPC is deemed safe for use in cosmetics. Naturally, for any new product, we always advise brands to conduct patch testing on the final formulation to ensure maximum consumer safety.
Q2: What distinguishes grape seed extract standardised to 95% OPC from that standardised to 95% polyphenols? Which is superior?
A2: Whilst OPCs belong to the polyphenol family, the "95% OPC" standardisation protocol is significantly more precise and stringent than "95% polyphenols". Products labelled "95% polyphenols" may contain higher proportions of other phenolic substances, whose bioactivity and skin permeability may be significantly inferior to OPCs. Therefore, for cosmetic formulations seeking premium efficacy, selecting products standardised to "95% OPC" represents a superior and more reliable choice.
Q3: Does colour pose an issue when incorporating Grape Seed Extract 95% OPC into formulations? How might this be addressed?
A3: Grape Seed Extract 95% OPC is inherently a reddish-brown powder. When added to formulations, it imparts a natural hue ranging from pale yellow to light brown, depending on the concentration. For formulations requiring a pure white appearance, this can be managed through:
1) Reduce the dosage and utilise it as a supplementary antioxidant;
2) Employ encapsulation technology for colour adjustment;
3) Incorporate it into tinted products such as foundation, tinted moisturisers, or rinse-off masks where colour impact is minimal. Grape Seed Extract 95% OPC, with its versatility and high compatibility, can be widely applied across diverse cosmetic formulations, empowering brands to create star products with exceptional efficacy.
Reference
[1]Sean X. Liu, Elizabeth White. "Extraction and Characterisation of Proanthocyanidins from Grape Seeds." The Open Food Science Journal (2012).
[2]Yumiko Nakamura, S. Tsuji et al. "Analysis of Proanthocyanidins in Grape Seed Extracts, Health Foods and Grape Seed Oils." Journal of Health Science (2003).
[3]Baoshan Sun, M. I. Spranger. "Quantitative extraction and analysis of grape and wine proanthocyanidins and stilbenes: review." Ciencia E Tecnica Vitivinicola (2005).
[4]Ximena Terra Barbadora. "GRAPE-SEED PROCYANIDINS AS ANTI-INFLAMMATORY AGENTS." (2009).
[5]Zhang Yue-ping. "Purification and detection of the proanthocyanidins from the grape seed extracts." Food Science and Technology International (2009).

